scholarly journals The Importance of Optical Coherence Tomography and Autofluorescence in the Documentation of Papillary Colobomatous Fossette

2021 ◽  
pp. 19-23
Author(s):  
Thiago Sande Miguel ◽  
Vinicius Sande Miguel ◽  
Tais Cristina Rossett ◽  
Daniel Almeida da Costa ◽  
Maurício Bastos Pereira
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Disc ◽  
Present Report ◽  
Serous Retinal Detachment ◽  
Male Student ◽  
Lamina Cribrosa ◽  
Optical Coherence ◽  
Topical Medication ◽  
Visual Complaints

Aims: To describe the importance of optical coherence tomography and autofluorescence in the documentation of papillary colobomatous fossette. Presentation of Case: F.D.O. A 14-year-old male student is referred for evaluation of the fundus of the eye due to an alteration in the optic disc noticed by another professional who did not feel safe in the follow-up. The patient was completely asymptomatic at the time of the consultation and did not claim previous visual complaints. She denied systemic and ocular comorbidities and did not use any systemic and topical medication. Discussion: The congenital optic disc pit is a rare and typically unilateral congenital anomaly, consisting of a retinal herniation that extends into the subarachnoid space through a lamina cribrosa defect. 8,13,15,16 Although this condition, in most cases, does not present complications and remains asymptomatic, it can sometimes worsen with a significant decrease in visual acuity. This more serious condition can be characterized by important macular alterations, such as serous retinal detachment, cystic degenerations and degenerative pigmentary alterations. 14,16,17,18 The patient in the present report did not have any visual complaints and did not present severe structural and functional retinal damage, which highlights the importance of early diagnosis. Conclusions: The colobomatous papilla pit is characterized by the presence of isolated cavities in the optic disc head secondary to a developmental disorder of the primitive epithelial papilla. Its incidence is 1:10,000 people without sexual or racial predilection. It presents, in most cases, asymptomatic, unilateral in 85-95% of cases and rarely with more than one pit per disc.

Multimodal imaging of optic disc melanocytoma

2021 ◽  
pp. 112067212110106
Author(s):  
Cinzia Mazzini ◽  
Giulio Vicini ◽  
Cristina Nicolosi ◽  
Giulia Pieretti ◽  
Stanislao Rizzo
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Disc ◽  
Multimodal Imaging ◽  
Fundus Autofluorescence ◽  
Case Series ◽  
Optical Coherence ◽  
Retrospective Case ◽  
Swept Source ◽  
Rule Out

Purpose: To describe the findings of four patients (four eyes) with optic disc melanocytoma (ODM), using multimodal imaging. Methods: Retrospective case series. Results: On ocular ultrasonography ODMs appeared as hyperechogenic lesions with moderate-to-high internal reflectivity. On blue-light fundus autofluorescence, ODMs showed total hypoautofluorescence, while, on infrared reflectance images appeared as bright and well-marginated lesions. MultiColor composite images showed reddish-brown lesions with well-defined margins. Swept-source optical coherence tomography revealed elevated lesions covering the optic disc with an irregular hyperreflective surface, dishomogeneous internal structure with hyperreflective dots, and posterior shadowing. In all cases optical coherence tomography angiography detected intratumoral blood vessels which were not detectable with fluorescein angiography. Conclusion: Multimodal imaging in ODM might be useful both at presentation, increasing the diagnostic accuracy, and at follow-up, providing helpful details, that can help to rule out the possibility of malignant transformation and other ocular complications.

scholarly journals Effects of myopia and glaucoma in the prelaminar neural canal and anterior lamina cribrosa using 1060-nm swept-source OCT

2021 ◽  
Author(s):  
Sieun Lee ◽  
Morgan Heisler ◽  
Dhanashree Ratra ◽  
Vineet Ratra ◽  
Paul J Mackenzie ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Field ◽  
Optic Disc ◽  
Open Angle Glaucoma ◽  
Lamina Cribrosa ◽  
Optical Coherence ◽  
Inclusion Criteria ◽  
Swept Source ◽  
Neural Canal ◽  
Sd Oct

Purpose: Investigate the effects of myopia and glaucoma in the prelaminar neural canal and anterior lamina cribrosa using 1060-nm swept-source optical coherence tomography Design: Retrospective, cross-sectional study Methods: - Setting: Clinical practice - Patient or study population: 19 controls (38 eyes); 38 glaucomatous subjects (63 eyes). Inclusion criteria for glaucomatous subjects: i) optic disc neural rim loss; ii) peripapillary nerve fibre layer (NFL) loss on spectral domain optical coherence tomography (SD-OCT); iii) glaucomatous visual field defect with an abnormal pattern standard deviation (P<.05); iv) stable SD-OCT, visual field, and optic disc clinical examination for 6 or more months. Inclusion criteria for control subjects: no evidence of retinal or optic nerve pathology. Exclusion criteria: i) retinal diseases or optic neuropathy other than primary open-angle glaucoma; ii) intraocular pressure ≤ 10 mmHg or ≥ 20 mmHg; iii) ocular media opacities; iv) any surgery-related complication deemed inappropriate for the study. - Intervention or observation procedures: Swept-source optical coherence tomography - Main Outcome Measure(s): Bruchs membrane opening (BMO) and anterior laminar insertion (ALI) dimension, prelaminar neural canal dimension, anterior lamina cribrosa surface (ALCS) depth Results: Glaucomatous eyes had more bowed and nasally rotated BMO and ALI, more horizontally skewed prelaminar neural canal, and deeper ALCS than the control eyes. Increased axial length was associated with a wider, longer, and more horizontally skewed neural canal, and decrease in the ALCS depth and curvature. Conclusion: Our findings suggest that glaucomatous posterior bowing or cupping of lamina cribrosa can be significantly confounded by the myopic expansion of the neural canal. This may be related to higher glaucoma risk associated with myopia from decreased compliance and increased susceptibility to IOP-related damage of LC being pulled taut.

scholarly journals Re-evaluating diabetic papillopathy using optical coherence tomography and inner retinal sublayer analysis

Eye ◽  
2021 ◽  
Author(s):  
Josef Huemer ◽  
Hagar Khalid ◽  
Daniel Ferraz ◽  
Livia Faes ◽  
Edward Korot ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Optic Disc ◽  
Case Series ◽  
Retinal Nerve Fibre Layer ◽  
Optical Coherence ◽  
Patients With Diabetes ◽  
Optic Disc Swelling ◽  
The Mean

Abstract Background/Objectives To re-evaluate diabetic papillopathy using optical coherence tomography (OCT) for quantitative analysis of the peripapillary retinal nerve fibre layer (pRNFL), macular ganglion cell layer (mGCL) and inner nuclear layer (mINL) thickness. Subjects/Methods In this retrospective observational case series between June 2008 and July 2019 at Moorfields Eye hospital, 24 eyes of 22 patients with diabetes and optic disc swelling with confirmed diagnosis of NAION or diabetic papillopathy by neuro-ophthalmological assessment were included for evaluation of the pRNFL, mGCL and mINL thicknesses after resolution of optic disc swelling. Results The mean age of included patients was 56.5 (standard deviation (SD) ± 14.85) years with a mean follow-up duration of 216 days. Thinning of pRNFL (mean: 66.26, SD ± 31.80 µm) and mGCL (mean volume: 0.27 mm3, SD ± 0.09) were observed in either group during follow-up, the mINL volume showed no thinning with 0.39 ± 0.05 mm3. The mean decrease in visual acuity was 4.13 (SD ± 14.27) ETDRS letters with a strong correlation between mGCL thickness and visual acuity (rho 0.74, p < 0.001). Conclusion After resolution of acute optic disc swelling, atrophy of pRNFL and mGCL became apparent in all cases of diabetic papillopathy and diabetic NAION, with preservation of mINL volumes. Analysis of OCT did not provide a clear diagnostic distinction between both entities. We suggest a diagnostic overlay with the degree of pRNFL and mGCL atrophy of prognostic relevance for poor visual acuity independent of the semantics of terminology.

WED 014 Oct minimises unnecessary investigation for suspected papilloedema

2018 ◽  
Vol 89 (10) ◽  
pp. A3.1-A3
Author(s):  
Coysh Thomas ◽  
Whiteside David ◽  
Williamson Sarah ◽  
Muhammed Louwai ◽  
Metta Vinod ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Lumbar Puncture ◽  
Optic Disc ◽  
Optical Coherence ◽  
The Impact ◽  
Optic Discs

BackgroundOptical coherence tomography (OCT) is a rapid and painless way to provide a record of the optic disc structure. Though not specific, it can identify swollen optic discs. We determined the impact of OCT prior to referral on the pathway for managing suspected papilloedema.MethodsAudit of adults referred from the Western Eye Hospital to St Mary’s Hospital with suspected papilloedema was performed between 1/1/17 and 16/5/17. A follow-up re-audit was performed from 1/6/17 to 31/8/17 following implementation of OCT prior to referral.ResultsThe initial audit identified 50 patients over 136 days and the re-audit 26 patients over 92 days. In the initial audit 6/50 had OCT and 17/50 (34%) were admitted. 6/50 patients were subsequently found not to have papilloedema on fundoscopy, none of whom had OCT. 4/6 underwent unnecessary neuroimaging and lumbar puncture. 3 were admitted, equating to 18% of all admissions, for an average of 2.3 days. In the re-audit all had OCT, 6/26 (23%) were admitted and none were subsequently found not to have papilloedema.ConclusionUse of OCT prior to referral for suspected papilloedema helps to reduce unnecessary investigations.

Choroidal metastasis follow-up during polychemotherapy (clinical case)

2021 ◽  
pp. 94-98
Author(s):  
A.S. Stoyukhina ◽  
Keyword(s):  
Optical Coherence Tomography ◽  
Key Words ◽  
Clinical Case ◽  
Correct Diagnosis ◽  
Optical Coherence ◽  
Choroidal Metastasis ◽  
Visual Complaints

Diagnosis of intraocular metastases does not cause difficulties in cases of oncological anamnesis in patient withs visual complaints and a characteristic ophthalmoscopic picture. In 10-20% of cases, eccentrically located metastases, are an accidental finding, which can cause difficulties in correct diagnosis establishing. A clinical case of asymptomatic bilateral multifocal choroidal metastases of small sizes is presented. Their OCT findings and the dynamics of follow-up during polychemotherapy are described. Key words: choroidal metastasis, optical coherence tomography, polychemotherapy.

scholarly journals Detection of Superficial and Buried Optic Disc Drusen With Swept-source Optical Coherence Tomography

2021 ◽  
Author(s):  
Xiaohong Guo ◽  
Yingjie Wu ◽  
Yuhong Wu ◽  
Hui Liu ◽  
Shuai Ming ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Disc ◽  
Fundus Autofluorescence ◽  
Lamina Cribrosa ◽  
Fundus Photography ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Swept Source ◽  
Imaging Characteristics ◽  
Optic Disc Drusen

Abstract Background To detect the superficial and buried optic disc drusen (ODD) with swept-source optical coherence tomography (SS-OCT).Methods Retrospective cross-sectional study.Twenty patients (age 18-74 years) diagnosed with ODD via B-scan ultrasonography were analysed. All patients underwent color fundus photography (CFP), B-scan ultrasonography, fundus autofluorescence (FAF), and SS-OCT.We defined each hyporeflective signal mass of SS-OCT as an ODD, recorded its location and relationship with Bruch’s membrane opening (BMO), and other ophthalmic imaging characteristics.Results 20 (33 eyes) patients had 54 ODDs in all, except one eye did not show abnormal optic disc findings on SS-OCT. We classified ODD into three categories: ODD above BMO, ODD across BMO, and ODD below BMO. The ODDs across BMO were the largest, followed by ODDs below BMO, and those above BMO. The location of the ODDs: One (1.9%) was in the border tissue of Elschnig, 6 (11.1%) might span across the lamina cribrosa, 16 (29.6%) were above BMO located in the neuroepithelial layer, 9 (16.7%) spanned across BMO located near the center of the optic disc, 18 (33.3%) were below BMO located near the center of the optic disc, 4 (7.4%) were below BMO located within the optic disc rim. When the anterior margin was ≥ 100 μm from the BMO, clear autofluorescence could be seen. Conclusion Multimodal imaging provided a deeper understanding of ODD. SS-OCT illustrated more details about the relationship between the posterior surface of ODD, BMO and the lamina cribrosa.

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