Contrary to P(V) compounds, As(V) compounds can very easily reduced by thiols to As(III) thiolates that are deemed to play a central role in the metabolism of arsenic and therefore a review on the preparation and properties of the title thiolates can be of interest. The preparation of trithioarsenites, dithioarsonites and thioarsinites involves reactions of a thiol with a proper As(V) or As(III) precursor via 4-centered transition states or a thiolate by SN2 mechanisms. Convenient precursors are the solids As2O3, arsonic and arsinic acids, although for the latter two acids the separation of the product from the co-produced disulfides can be problematic. Only a few crystal structures have been reported and involve only trithioarsenites. From their chemical properties, the hydrolyses, transthiolations and air oxidations are of particular interest from mechanistic and biochemical/biological points of view. Their nucleophilicity towards alkyl halides and acyl derivatives revealed unexpected behavior. Although these molecules have many free electron pairs only three reports were found pertaining to their reaction with metal cations (Hg2+) and metal carbonyls; the mercuric complexes being not characterized. Only a few studies appeared for the action of the title compounds towards enzymes, while the patent literature revealed that they have bactericidal, fungicidal and insecticidal activities for agricultural applications, some have antiparasitic activity on animals and a few are carcinostatic.
Reactions of the Unsaturated Methyl-Bridged Complexes [Mo2Cp2(μ-CH3)(μ-P Bu2)(CO)x] (x = 1, 2) Towards Transition Metal Carbonyls: Convenient Dehydrogenative Route to Heterometallic Methylidyne-Bridged Clusters
