Recent Advances in the Chemistry and Synthesis of Thienopyrazine, Pyrrolopyrazine and Furopyrazine Derivatives

Bicyclic compounds derived from pyrazine and aromatic five-membered heterocycles including thiophene, furan and pyrrole show various biological and pharmacological proBicyclic compounds derived from pyrazine and aromatic five-membered heterocycles including thiophene, furan and pyrrole show various biological and pharmacological properties, such as anti-inflammatory, antiviral, antitumor, antioxidant, antimycobacterial, and cytostatic activities. In many cases, it has been demonstrated that there are more potent cytostatic and cytotoxic agents against human tumor cell lines, leukemia, colon cancer, central nervous system cancer, melanoma, ovarian cancer, prostate cancer and breast cancer. They are also useful precursors for the large scale preparation of inorganicorganic hybrid solar cells, suitable acceptors for the synthesis of low-band gap polymers. They use ligands for serotoninergic 5-HT7 receptor and are effective in neurogical and psychiatric diseases, antimalarial, neuroleptic and cardiovascular. The absence of any useful review concerning the chemistry and synthesis of the above-mentioned heterocyles encouraged us to underscore the recent advances in chemistry and synthetic approaches leading to the preparation of thienopyrazines, pyrrolopyrazines and furopyrazines since 1990.perties such as anti-inflammatory, antiviral, antitumor, antioxidant, antimycobacterial, and cytostatic activities. In many cases, it has been demonstrated that they are much more potent cytostatic and cytotoxic agents against human tumor cell lines, leukemia, colon cancer, central nervous system cancer, melanoma, ovarian cancer, prostate cancer and breast cancer. They also are useful precursors for the large scale preparation of inorganic-organic hybrid solar cells, suitable acceptors for the synthesis of low-band gap polymers. They use as ligands for serotoninergic 5-HT7 receptor and being effective in neurogical and psychiatric diseases, antimalarial, neuroleptic and cardiovascular. Due to the absence of any useful review concerning the chemistry and synthesis of the above-mentioned heterocyles encouraged us to underscore the recent advances in the chemistry and synthetic approaches leading to preparation of thienopyrazines, pyrrolopyrazines and furopyrazines from 1990 up to date.

Design and synthesis of N-substituted perylene diimide based low band gap polymers for organic solar cell applications

Newly designed N-substituted perylene diimide based acceptor copolymers have been characterized and tested for organic solar cells with P3HT in different weight ratios.

The integrated adjustment of chlorine substitution and two-dimensional side chain of low band gap polymers in organic solar cells

The chlorination and side-chain extension of benzothiadiazole derivatives can finely manipulate the open-circuit voltage in their solar cells.