Seismic images produced by migration of seismic data related to complex geologies, suchas pre-salt environments, are often contaminated by artifacts due to the presence of multipleinternal reflections. These reflections are created when the seismic wave is reflected morethan once in a source-receiver path and can be interpreted as the main coherent noise inseismic data. Several schemes have been developed to predict and subtract internal multiplereflections from measured data, such as the Marchenko multiple elimination (MME) scheme,which eliminates the referred events without requiring a subsurface model or an adaptivesubtraction approach. The MME scheme is data-driven, can remove or attenuate mostof these internal multiples, and was originally based on the Neumann series solution ofMarchenko’s projected equations. However, the Neumann series approximate solution isconditioned to a convergence criterion. In this work, we propose to formulate the MMEas a least-squares problem (LSMME) in such a way that it can provide an alternative thatavoids a convergence condition as required in the Neumann series approach. To demonstratethe LSMME scheme performance, we apply it to 2D numerical examples and compare theresults with those obtained by the conventional MME scheme. Additionally, we evaluatethe successful application of our method through the generation of in-depth seismic images,by applying the reverse-time migration (RTM) algorithm on the original data set and tothose obtained through MME and LSMME schemes. From the RTM results, we show thatthe application of both schemes on seismic data allows the construction of seismic imageswithout artifacts related to internal multiple events.