recombinant cho cells
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scholarly journals Increasing transgene expression and stability in recombinant CHO cells with DNA methyltransferase Dnmt3b gene knockout via CRISPR/Cas9

2021 ◽  
Vol 35 (S1) ◽  
Author(s):  
Ying‐Ying Feng ◽  
Jiang‐Tao Lu ◽  
Meng‐Ke Xiao ◽  
Yan‐Long Jia ◽  
Tian‐Yun Wang
Keyword(s):  
Cho Cells ◽  
Transgene Expression ◽  
Dna Methyltransferase ◽  
Gene Knockout ◽  
Recombinant Cho Cells ◽  
Dnmt3b Gene

scholarly journals Zinc supplementation increases protein titer of recombinant CHO cells

2019 ◽  
Vol 71 (5) ◽  
pp. 915-924 ◽  
Author(s):  
Berta Capella Roca ◽  
Antonio Alarcón Miguez ◽  
Joanne Keenan ◽  
Srinivas Suda ◽  
Niall Barron ◽  
...  
Keyword(s):  
Cho Cells ◽  
Zinc Supplementation ◽  
Recombinant Cho Cells

scholarly journals Revealing Key Determinants of Clonal Variation in Transgene Expression in Recombinant CHO Cells Using Targeted Genome Editing

2018 ◽  
Vol 7 (12) ◽  
pp. 2867-2878 ◽  
Author(s):  
Jae Seong Lee ◽  
Jin Hyoung Park ◽  
Tae Kwang Ha ◽  
Mojtaba Samoudi ◽  
Nathan E. Lewis ◽  
...  
Keyword(s):  
Genome Editing ◽  
Cho Cells ◽  
Transgene Expression ◽  
Clonal Variation ◽  
Recombinant Cho Cells

Effect of Environmental Parameters on Glycosylation of Recombinant Immunoglobulin G Produced from Recombinant CHO Cells

2018 ◽  
Vol 23 (4) ◽  
pp. 456-464 ◽  
Author(s):  
Seong-Min Kim ◽  
Kyu-Ho Chang ◽  
Duk Jae Oh
Keyword(s):  
Immunoglobulin G ◽  
Cho Cells ◽  
Environmental Parameters ◽  
Recombinant Cho Cells

scholarly journals A BioDesign Approach to Obtain High Yields of Biosimilars by Anti-apoptotic Cell Engineering: a Case Study to Increase the Production Yield of Anti-TNF Alpha Producing Recombinant CHO Cells

2017 ◽  
Vol 184 (1) ◽  
pp. 303-322 ◽  
Author(s):  
Sultan Gulce Iz ◽  
Muge Anil Inevi ◽  
Pelin Saglam Metiner ◽  
Duygu Ayyildiz Tamis ◽  
Nazli Kisbet
Keyword(s):  
Cho Cells ◽  
Apoptotic Cell ◽  
Cell Engineering ◽  
Production Yield ◽  
Tnf Alpha ◽  
Recombinant Cho Cells ◽  
High Yields

scholarly journals Low glucose concentrations within typical industrial operating conditions have minimal effect on the transcriptome of recombinant CHO cells

2017 ◽  
Vol 33 (3) ◽  
pp. 771-785 ◽  
Author(s):  
Yogender Kumar Gowtham ◽  
Christopher A. Saski ◽  
Sarah W. Harcum
Keyword(s):  
Cho Cells ◽  
Operating Conditions ◽  
Minimal Effect ◽  
Recombinant Cho Cells ◽  
Low Glucose

scholarly journals Proteomic differences in recombinant CHO cells producing two similar antibody fragments

2016 ◽  
Vol 113 (9) ◽  
pp. 1902-1912 ◽  
Author(s):  
Wolfgang Sommeregger ◽  
Patrick Mayrhofer ◽  
Willibald Steinfellner ◽  
David Reinhart ◽  
Michael Henry ◽  
...  
Keyword(s):  
Cho Cells ◽  
Antibody Fragments ◽  
Recombinant Cho Cells

Mannose metabolism in recombinant CHO cells and its effect on IgG glycosylation

2016 ◽  
Vol 113 (7) ◽  
pp. 1468-1480 ◽  
Author(s):  
Peter G. Slade ◽  
R. Guy Caspary ◽  
Shilpa Nargund ◽  
Chung-Jr Huang
Keyword(s):  
Cho Cells ◽  
Recombinant Cho Cells ◽  
Mannose Metabolism ◽  
Igg Glycosylation

Purification of TNFR-Fc produced in recombinant CHO cells: Characterization of product-related impurities

2015 ◽  
Vol 50 (8) ◽  
pp. 1313-1317 ◽  
Author(s):  
Kyung Hyun Min ◽  
Gyun Min Lee
Keyword(s):  
Cho Cells ◽  
Recombinant Cho Cells ◽  
Related Impurities
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