Novel cationic meso-CF3 BODIPY-based AIE fluorescent rotors for imaging viscosity in mitochondria

Two novel meso-CF3 BODIPY-based fluorescent rotors have been rationally prepared and sensitively respond to viscosity in living cells with fluorescence “turn-on” effect, attributing to the special restricted rotation of meso-CF3...

Suppression of Chain Transfer via Restricted Rotation Effect of Dibenzosuberyl Substituents in Polymerization Catalysis

The introduction of bulky ortho-steric substituents into α-diimine Ni(II) and Pd(II) species has been often used as an effective strategy to retard the chain transfer in olefin polymerization. In this...

Atropisomerism in Styrene: Synthesis, Stability, and Applications

Atropisomeric styrenes are a class of optically active compounds, the chirality of which results from restricted rotation of the C(vinyl)–C(aryl) single bond. In comparison with biaryl atropisomers, the less rigid skeleton of styrenes usually leads them to have lower rotational barriers. Although it has been overlooked for a long time, scientists have paid attention to this class of unique molecules in recent years and have developed many methods for the preparation of optically active atropisomeric styrenes. In this article, we review the development of the concept of atropisomeric styrenes, along with their isolation, asymmetric synthesis, and synthetic applications.1 Introduction2 The Concept of Styrene Atropisomerism3 Early Research: Separation of Optically Active Styrenes4 Synthesis of Optically Active Styrenes5 Stability of the Chirality of Atropisomeric Styrenes6 Outlook

Diastereoselective synthesis of atropisomeric pyrazolyl pyrrolo[3,4-d]isoxazolidines via pyrazolyl nitrone cycloaddition to facially divergent maleimides: intensive NMR and DFT studies

Diastereoselective pyrazole-based atropisomeric cycloadducts were formed by cycloaddition of a pyrazole-based nitrone and maleimides with restricted rotation around C–N bond caused by bulk ortho substitution.

Restricted rotation of an Fe(CO)2(PL3)-subunit in [FeFe]-hydrogenase active site mimics by intramolecular ligation

Terminal ligand fixation by covalent linkage to the bridging bdt ligand hinders ligand rotations.