hypothalamic hamartomas
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Neurosurgery ◽  
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Constantin Tuleasca ◽  
Hussein Hamdi ◽  
Géraldine Daquin ◽  
Nathalie Villeneuve ◽  
Patrick Chauvel ◽  
...  

2021 ◽  
pp. 257-262
Author(s):  
Pantaleo Romanelli ◽  
Alfredo Conti

Neurology ◽  
2021 ◽  
pp. 10.1212/WNL.0000000000012773
Author(s):  
Nathan T. Cohen ◽  
J. Helen Cross ◽  
Alexis Arzimanoglou ◽  
Samuel F. Berkovic ◽  
John F. Kerrigan ◽  
...  

Hypothalamic hamartomas (HH) are rare, basilar developmental lesions with widespread comorbidities often associated with refractory epilepsy and encephalopathy. Imaging advances allow for early, even prenatal, detection. Genetic studies suggest mutations in GLI3 and other patterning genes are involved in HH pathogenesis. About 50-80% of children with HH suffer from severe rage and aggression and a majority of cases exhibit externalizing disorders. Behavioral disruption and intellectual disability may predate epilepsy. Neuropsychological, sleep and endocrine disorders are typical. The purpose of this paper is to provide a summary of the current understanding of HH, and to highlight opportunities for future research.


2021 ◽  
Vol 173 ◽  
pp. 106624
Author(s):  
Hussein Hamdi ◽  
Patrizia Ferrante ◽  
Giorgio Spatola ◽  
Wesley Clawson ◽  
Aileen McGonigal ◽  
...  

2021 ◽  
Vol 424 ◽  
pp. 117428
Author(s):  
Aditya M. Kondajji ◽  
Audree Evans ◽  
Meachelle Lum ◽  
Daniel Kulinich ◽  
Ansley Unterberger ◽  
...  

Epilepsia ◽  
2021 ◽  
Author(s):  
Hussein Hamdi ◽  
Faisal Albader ◽  
Giorgio Spatola ◽  
Virginie Laguitton ◽  
Agnes Trebuchon ◽  
...  

Seizure ◽  
2021 ◽  
Vol 86 ◽  
pp. 102-108
Author(s):  
Min Wang ◽  
Yi Zhang ◽  
Ping Xue ◽  
Yuanfeng Zhou ◽  
Wei Shi ◽  
...  

2021 ◽  
Vol 116 ◽  
pp. 107774
Author(s):  
Karim Mithani ◽  
Clemens Neudorfer ◽  
Alexandre Boutet ◽  
Jurgen Germann ◽  
Gavin J.B. Elias ◽  
...  

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