Primary tracheal schwannoma resected in a Turner syndrome patient: a case report

We report a case of primary tracheal schwannoma in a 31-year-old woman. She had a previous history of follicular thyroid carcinoma treated surgically and Turner syndrome. In a follow-up computed tomography scan, we found a partially obstructing intraluminal tracheal tumor, which was confirmed by bronchoscopy. The patient was treated by surgical resection and primary tracheal anastomosis. The tumor was 14 mm in diameter, with an intact capsule. Histologic analysis revealed a Schwann cell origin tumor.

A rare unbalanced Y:autosome translocation in a Turner syndrome patient

Background:Y:autosome translocations are reported to be associated with male infertility and azoospermia. Female cases with Y:autosome translocation are extremely rare.Case presentation:We report a unique case of a rare unbalanced translocation t(Y;13) in a 12-year-old girl with Turner syndrome. Combined cytogenetic testing helped to demonstrate the detail of rare chromosomal structural rearrangement in this patient.Conclusions:The presented case showed femaleness phenotype and failure of masculinization with presence of Y chromosome and theSRYgene. She was treated with growth hormone (GH) therapy after confirming the presence of only female internal gonad with laparoscopy.