Progressive knowledge of allergenic structures resulted in a broad
availability of allergenic molecules for diagnosis. Component resolved
diagnosis allowed a better understanding of patient sensitization
patterns, facilitating allergen immunotherapy decisions. In parallel to
the discovery of allergenic molecules, there was a progressive
development of a regulation framework that affected both in vitro
diagnostics and Allergen Immunotherapy products. With a progressive
understanding of underlying mechanisms associated to Allergen
immunotherapy and an increasing experience of application of molecular
diagnosis in daily life, we focus in analyzing the evidences of the
value provided by molecular allergology in daily clinical practice, with
a focus on Allergen Immunotherapy decissions.