bioreductive activation
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scholarly journals Structure of Ddn, the Deazaflavin-Dependent Nitroreductase from Mycobacterium tuberculosis Involved in Bioreductive Activation of PA-824

Structure ◽  
2013 ◽  
Vol 21 (1) ◽  
pp. 191 ◽  
Author(s):  
Susan E. Cellitti ◽  
Jennifer Shaffer ◽  
David H. Jones ◽  
Tathagata Mukherjee ◽  
Meera Gurumurthy ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Bioreductive Activation

The role of bioreductive activation of antitumour anthracycline drugs in cytotoxic activity against sensitive and multidrug resistant leukaemia HL60 cells

2012 ◽  
Vol 674 (2-3) ◽  
pp. 112-125 ◽  
Author(s):  
Dorota Kostrzewa-Nowak ◽  
Bohdan Bieg ◽  
Mark J.I. Paine ◽  
C. Roland Wolf ◽  
Jolanta Tarasiuk
Keyword(s):  
Cytotoxic Activity ◽  
Multidrug Resistant ◽  
Hl60 Cells ◽  
Bioreductive Activation

scholarly journals Structure of Ddn, the Deazaflavin-Dependent Nitroreductase from Mycobacterium tuberculosis Involved in Bioreductive Activation of PA-824

Structure ◽  
2012 ◽  
Vol 20 (1) ◽  
pp. 101-112 ◽  
Author(s):  
Susan E. Cellitti ◽  
Jennifer Shaffer ◽  
David H. Jones ◽  
Tathagata Mukherjee ◽  
Meera Gurumurthy ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Bioreductive Activation

scholarly journals Substrate specificity of the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis responsible for the bioreductive activation of bicyclic nitroimidazoles

FEBS Journal ◽  
2011 ◽  
Vol 279 (1) ◽  
pp. 113-125 ◽  
Author(s):  
Meera Gurumurthy ◽  
Tathagata Mukherjee ◽  
Cynthia S. Dowd ◽  
Ramandeep Singh ◽  
Pornwaratt Niyomrattanakit ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Substrate Specificity ◽  
Bioreductive Activation

ChemInform Abstract: Synthesis of Novel Paclitaxel Prodrugs Designed for Bioreductive Activation in Hypoxic Tumor Tissue.

ChemInform ◽  
2010 ◽  
Vol 33 (13) ◽  
pp. no-no
Author(s):  
Eric W. P. Damen ◽  
Tapio J. Nevalainen ◽  
Toine J. M. van den Bergh ◽  
Franciscus M. H. de Groot ◽  
Hans W. Scheeren
Keyword(s):  
Tumor Tissue ◽  
Hypoxic Tumor ◽  
Bioreductive Activation

Bioreductive activation of quinone antitumor drugs by mitochondrial voltage-dependent anion channel 1

2008 ◽  
Vol 83 (4) ◽  
pp. 261-266 ◽  
Author(s):  
Eriko Simamura ◽  
Hiroki Shimada ◽  
Yasuhito Ishigaki ◽  
Toshihisa Hatta ◽  
Nobuaki Higashi ◽  
...  
Keyword(s):  
Anion Channel ◽  
Antitumor Drugs ◽  
Voltage Dependent Anion Channel ◽  
Voltage Dependent ◽  
Bioreductive Activation
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