Bioreductive activation of mitoxantrone by NADPH cytochrome P450 reductase does not change its apoptotic stimuli properties in regard to sensitive and multidrug resistant leukaemia HL60 cells

Hl60 Cells ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Bioreductive Activation

Bioreductive activation of mitoxantrone by NADPH cytochrome P450 reductase. Implications for increasing its ability to inhibit the growth of sensitive and multidrug resistant leukaemia HL60 cells

Cancer Letters ◽

10.1016/j.canlet.2006.01.012 ◽

2007 ◽

Vol 245 (1-2) ◽

pp. 252-262 ◽

Cited By ~ 13

Author(s):

Dorota Kostrzewa-Nowak ◽

Mark J.I. Paine ◽

Anna Korytowska ◽

Katarzyna Serwatka ◽

Sylwia Piotrowska ◽

...

Keyword(s):

Cytochrome P450 ◽

Multidrug Resistant ◽

Hl60 Cells ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Bioreductive Activation

Role of structural factors of antitumour anthraquinone derivatives and analogues in the ability to undergo bioreductive activation by NADPH cytochrome P450 reductase. Implications for increasing the activity against sensitive and multidrug-resistant leukaemia HL60 cells

Anti-Cancer Drugs ◽

10.1097/cad.0b013e32834fcf4f ◽

2012 ◽

Vol 23 (4) ◽

pp. 393-405 ◽

Cited By ~ 5

Author(s):

Dorota Kostrzewa-Nowak ◽

Bohdan Bieg ◽

Mark J.I. Paine ◽

C. Roland Wolf ◽

Jolanta Tarasiuk

Keyword(s):

Cytochrome P450 ◽

Multidrug Resistant ◽

Structural Factors ◽

Hl60 Cells ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Anthraquinone Derivatives ◽

DNA damage induced by NADPH cytochrome P450 reductase-activated idarubicin in sensitive and multidrug resistant MCF7 breast cancer cells

Pharmacological Reports ◽

10.1016/j.pharep.2016.10.002 ◽

2017 ◽

Vol 69 (1) ◽

pp. 185-195 ◽

Cited By ~ 2

Author(s):

Wojciech Żwierełło ◽

Agnieszka Maruszewska ◽

Robert Nowak ◽

Dorota Kostrzewa-Nowak ◽

Jolanta Tarasiuk

Keyword(s):

Breast Cancer ◽

Dna Damage ◽

Cytochrome P450 ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Multidrug Resistant ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Probing the role of lysines and arginines in the catalytic function of cytochrome P450d by site-directed mutagenesis. Interaction with NADPH-cytochrome P450 reductase

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)67801-4 ◽

1991 ◽

Vol 266 (6) ◽

pp. 3372-3375

Author(s):

T Shimizu ◽

T Tateishi ◽

M Hatano ◽

Y Fujii-Kuriyama

Keyword(s):

Cytochrome P450 ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Catalytic Function ◽

The cytochrome P450 2B4-NADPH cytochrome P450 reductase electron transfer complex is not formed by charge-pairing.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)42093-5 ◽

1992 ◽

Vol 267 (21) ◽

pp. 14669-14676

Author(s):

A.I. Voznesensky ◽

J.B. Schenkman

Keyword(s):

Electron Transfer ◽

Cytochrome P450 ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Cytochrome P450 2B4 ◽

Electron Transfer Complex

Organization of NADPH-Cytochrome P450 Reductase and CYP1A2 in the Endoplasmic Reticulum—Microdomain Localization Affects Monooxygenase Function

Molecular Pharmacology ◽

10.1124/mol.110.068817 ◽

2010 ◽

Vol 79 (3) ◽

pp. 549-557 ◽

Cited By ~ 24

Author(s):

Lauren Brignac-Huber ◽

James R. Reed ◽

Wayne L. Backes

Keyword(s):

Endoplasmic Reticulum ◽

Cytochrome P450 ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Role of the prosthetic groups of NADPH-cytochrome P450 reductase in 3-hydroxyanthranilamide-catalyzed, NADPH-dependent superoxide anion production

Redox Report ◽

10.1080/13510002.1996.11747070 ◽

1996 ◽

Vol 2 (5) ◽

pp. 339-344

Author(s):

Y. Ohta ◽

R. Shinohara ◽

I. Ishiguro

Keyword(s):

Cytochrome P450 ◽

Superoxide Anion ◽

Superoxide Anion Production ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Anion Production ◽

Prosthetic Groups

Reduction of cytochrome b5 by NADPH–cytochrome P450 reductase

Archives of Biochemistry and Biophysics ◽

10.1016/j.abb.2005.06.019 ◽

2005 ◽

Vol 440 (2) ◽

pp. 204-211 ◽

Cited By ~ 56

Author(s):

F. Peter Guengerich

Keyword(s):

Cytochrome P450 ◽

Cytochrome B5 ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Altered heme catabolism by heme oxygenase-1 caused by mutations in human NADPH cytochrome P450 reductase

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2010.08.072 ◽

2010 ◽

Vol 400 (3) ◽

pp. 374-378 ◽

Cited By ~ 26

Author(s):

Amit V. Pandey ◽

Christa E. Flück ◽

Primus E. Mullis

Keyword(s):

Cytochrome P450 ◽

Heme Oxygenase ◽

Heme Oxygenase 1 ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Membrane Topology of NADPH–Cytochrome P450 Reductase on the Endoplasmic Reticulum

Archives of Biochemistry and Biophysics ◽

10.1006/abbi.1997.0553 ◽

1998 ◽

Vol 351 (2) ◽

pp. 175-179 ◽

Cited By ~ 22

Author(s):

Yuichiro Kida ◽

Satoru Ohgiya ◽

Katsuyoshi Mihara ◽

Masao Sakaguchi

Keyword(s):

Endoplasmic Reticulum ◽

Cytochrome P450 ◽

Membrane Topology ◽

Nadph Cytochrome ◽

P450 Reductase ◽