ScienceGate
Advanced Search
Author Search
Journal Finder
Blog
Sign in / Sign up
ScienceGate
Search
Author Search
Journal Finder
Blog
Sign in / Sign up
De Novo Design of Peptidic Positive Allosteric Modulators Targeting TRPV1 with Analgesic Effects (Adv. Sci. 17/2021)
Advanced Science
◽
10.1002/advs.202170104
◽
2021
◽
Vol 8
(17)
◽
pp. 2170104
Author(s):
Lizhen Xu
◽
Heng Zhang
◽
Yunfei Wang
◽
Xiancui Lu
◽
Zhenye Zhao
◽
...
Keyword(s):
De Novo
◽
De Novo Design
◽
Allosteric Modulators
◽
Analgesic Effects
◽
Positive Allosteric Modulators
Download Full-text
Related Documents
Cited By
References
De Novo Design of Peptidic Positive Allosteric Modulators Targeting TRPV1 with Analgesic Effects
Advanced Science
◽
10.1002/advs.202101716
◽
2021
◽
pp. 2101716
Author(s):
Lizhen Xu
◽
Heng Zhang
◽
Yunfei Wang
◽
Xiancui Lu
◽
Zhenye Zhao
◽
...
Keyword(s):
De Novo
◽
De Novo Design
◽
Allosteric Modulators
◽
Analgesic Effects
◽
Positive Allosteric Modulators
Download Full-text
Faculty Opinions recommendation of Chimeric glutamate receptor subunits reveal the transmembrane domain is sufficient for NMDA receptor pore properties but some positive allosteric modulators require additional domains.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.726673095.793523203
◽
2016
◽
Author(s):
Robert Peoples
Keyword(s):
Nmda Receptor
◽
Glutamate Receptor
◽
Transmembrane Domain
◽
Allosteric Modulators
◽
Positive Allosteric Modulators
◽
Pore Properties
Download Full-text
Faculty Opinions recommendation of De novo design and engineering of non-ribosomal peptide synthetases.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.732289314.793543076
◽
2018
◽
Author(s):
Wenjun Zhang
◽
William Porterfield
Keyword(s):
De Novo
◽
De Novo Design
◽
Peptide Synthetases
Download Full-text
SAR Studies on mGlu5 Receptor Positive Allosteric Modulators (2003- 2013)
Current Topics in Medicinal Chemistry
◽
10.2174/1568026614666140826120419
◽
2014
◽
Vol 14
(15)
◽
pp. 1789-1841
◽
Cited By ~ 3
Author(s):
Junliang Hao
◽
Hui Xiong
Keyword(s):
Allosteric Modulators
◽
Sar Studies
◽
Positive Allosteric Modulators
Download Full-text
Molecular Modeling, de novo Design and Synthesis of a Novel, Extracellular Binding Fibroblast Growth Factor Receptor 2 Inhibitor Alofanib (RPT835)
Medicinal Chemistry
◽
10.2174/1573406412666160106154726
◽
2016
◽
Vol 12
(4)
◽
pp. 303-317
◽
Cited By ~ 6
Author(s):
Ilya Tsimafeyeu
◽
Frits Daeyaert
◽
Jean-Baptiste Joos
◽
Koen V. Aken
◽
John Ludes-Meyers
◽
...
Keyword(s):
Molecular Modeling
◽
Growth Factor
◽
Fibroblast Growth Factor
◽
Fibroblast Growth Factor Receptor
◽
De Novo
◽
Growth Factor Receptor
◽
De Novo Design
◽
Fibroblast Growth
◽
Design And Synthesis
Download Full-text
Exploration of Novel MTH1 Inhibitors Using Fragment-Based de novo Design, Virtual Screening, and Reverse Virtual Screening Methods
Биоорганическая химия
◽
10.1134/s0132342319040146
◽
2019
◽
Vol 45
(4)
◽
pp. 391-391
Author(s):
Xin-yu Zhao
◽
Kai Liu
◽
Xiao-li Wang
◽
Ri-lei Yu
◽
Cong-min Kang
Keyword(s):
Virtual Screening
◽
De Novo
◽
De Novo Design
◽
Screening Methods
◽
Reverse Virtual Screening
Download Full-text
Towards the de novo design of DNA based catalytic sites using a combined NMR and in silico approach
Collection Symposium Series
◽
10.1135/css201414151
◽
2014
◽
Author(s):
Dieter Buyst
◽
V. Gheerardijn
◽
J. Van Den Begin
◽
A. Madder
◽
J. C. Martins
Keyword(s):
In Silico
◽
De Novo
◽
De Novo Design
◽
Catalytic Sites
Download Full-text
A Promising Chemical Series of Positive Allosteric Modulators of the μ-Opioid Receptor that Enhance the Antinociceptive Efficacy of Opioids but not their Adverse Effects
Neuropharmacology
◽
10.1016/j.neuropharm.2021.108673
◽
2021
◽
pp. 108673
Author(s):
Kerri D. Pryce
◽
Hye Jin Kang
◽
Farhana Sakloth
◽
Yongfeng Liu
◽
Susan Khan
◽
...
Keyword(s):
Adverse Effects
◽
Opioid Receptor
◽
Allosteric Modulators
◽
Μ Opioid Receptor
◽
Positive Allosteric Modulators
Download Full-text
De Novo Design of Selective Quadruplex‐Duplex Junction Ligands and Structural Characterisation of their Binding Mode: Targeting the G4 Hot‐Spot
Chemistry - A European Journal
◽
10.1002/chem.202005026
◽
2020
◽
Author(s):
Laura Díaz-Casado
◽
Israel Serrano-Chacón
◽
Laura Montalvillo-Jiménez
◽
Francisco Corzana
◽
Agatha Bastida
◽
...
Keyword(s):
De Novo
◽
Hot Spot
◽
Binding Mode
◽
De Novo Design
◽
Structural Characterisation
Download Full-text
De novo design of modular and tunable protein biosensors
Nature
◽
10.1038/s41586-021-03258-z
◽
2021
◽
Author(s):
Alfredo Quijano-Rubio
◽
Hsien-Wei Yeh
◽
Jooyoung Park
◽
Hansol Lee
◽
Robert A. Langan
◽
...
Keyword(s):
De Novo
◽
De Novo Design
Download Full-text
Sign in / Sign up
Close
Export Citation Format
Close
Share Document
Close