cluster modeling
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2021 ◽  
Vol 385 ◽  
pp. 317-326
Author(s):  
Peng Huang ◽  
Yuhang Zhou ◽  
Yifei Ding ◽  
Qiuhua Miao ◽  
Minping Jia ◽  
...  


PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0241868
Author(s):  
Zachary D. Rethorn ◽  
Alessandra N. Garcia ◽  
Chad E. Cook ◽  
Oren N. Gottfried

Objectives Our objective was to analyze the collective effect of social determinants of health (SDoH) on lumbar spine surgery outcomes utilizing two different statistical methods of combining variables. Methods This observational study analyzed data from the Quality Outcomes Database, a nationwide United States spine registry. Race/ethnicity, educational attainment, employment status, insurance payer, and gender were predictors of interest. We built two models to assess the collective influence of SDoH on outcomes following lumbar spine surgery—a stepwise model using each number of SDoH conditions present (0 of 5, 1 of 5, 2 of 5, etc) and a clustered subgroup model. Logistic regression analyses adjusted for age, multimorbidity, surgical indication, type of lumbar spine surgery, and surgical approach were performed to identify the odds of failing to demonstrate clinically meaningful improvements in disability, back pain, leg pain, quality of life, and patient satisfaction at 3- and 12-months following lumbar spine surgery. Results Stepwise modeling outperformed individual SDoH when 4 of 5 SDoH were present. Cluster modeling revealed 4 distinct subgroups. Disparities between the younger, minority, lower socioeconomic status and the younger, white, higher socioeconomic status subgroups were substantially wider compared to individual SDoH. Discussion Collective and cluster modeling of SDoH better predicted failure to demonstrate clinically meaningful improvements than individual SDoH in this cohort. Viewing social factors in aggregate rather than individually may offer more precise estimates of the impact of SDoH on outcomes.





2019 ◽  
Vol 41 (8) ◽  
pp. 751-758 ◽  
Author(s):  
Frederik Bader ◽  
Tilen Lindic ◽  
Beate Paulus


Author(s):  
Валерий Еськов ◽  
Valeriy Es'kov ◽  
В. Галкин ◽  
V. Galkin ◽  
Д. Хвостов ◽  
...  
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2019 ◽  
Vol 55 (95) ◽  
pp. 14327-14330 ◽  
Author(s):  
Yufei Zhang ◽  
Daigo Masuzaki ◽  
Fumitaka Mafuné

Isolated CaMn4O5+ was hardly formed in the presence of oxygen, whereas CaMn4O4(OH)2+ was formed stably in the presence of water.



2019 ◽  
Vol 21 (40) ◽  
pp. 22385-22389
Author(s):  
Shaonan Dong ◽  
Shuping Bi

Quantum chemical cluster modeling suggests that both a symmetrical solvation environment and bulk solvent are necessary for proton rattling in water.



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