Matrix inversion is one of the most significant operations on a matrix. For any non-singular matrix A∈Zn×n, the inverse of this matrix may contain countless numbers of non-integer entries. These entries could be endless floating-point numbers. Storing, transmitting, or operating such an inverse could be cumbersome, especially when the size n is large. The only square integer matrix that is guaranteed to have an integer matrix as its inverse is a unimodular matrix U∈Zn×n. With the property that det(U)=±1, then U−1∈Zn×n is guaranteed such that UU−1=I, where I∈Zn×n is an identity matrix. In this paper, we propose a new integer matrix G˜∈Zn×n, which is referred to as an almost-unimodular matrix. With det(G˜)≠±1, the inverse of this matrix, G˜−1∈Rn×n, is proven to consist of only a single non-integer entry. The almost-unimodular matrix could be useful in various areas, such as lattice-based cryptography, computer graphics, lattice-based computational problems, or any area where the inversion of a large integer matrix is necessary, especially when the determinant of the matrix is required not to equal ±1. Therefore, the almost-unimodular matrix could be an alternative to the unimodular matrix.