preneoplastic foci
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scholarly journals Altered methylation of specific DNA loci in the liver of Bhmt‐null mice results in repression of Iqgap2 and F2rl2 and is associated with development of preneoplastic foci

2017 ◽  
Vol 31 (5) ◽  
pp. 2090-2103 ◽  
Author(s):  
Daniel S. Lupu ◽  
Luz D. Orozco ◽  
Ying Wang ◽  
John M. Cullen ◽  
Matteo Pellegrini ◽  
...  
Keyword(s):  
Preneoplastic Foci

scholarly journals Effects of sorafenib and cisplatin on preneoplastic foci of altered hepatocytes in fetal turkey liver

2017 ◽  
Vol 6 (1) ◽  
pp. 54-62
Author(s):  
Bettina Kaestner ◽  
Karsten Spicher ◽  
Ulrich Jaehde ◽  
Harald Enzmann
Keyword(s):  
Cell Proliferation ◽  
Promotion Effect ◽  
Preneoplastic Foci ◽  
Foci Of Altered Hepatocytes

Foci of altered hepatocytes (FAH) were induced in fetal turkey liver (FTL) by diethyl nitrosamine. Sorafenib but not cisplatin enhanced the development of FAH by increasing cell proliferation. This is indicative of a potential promotion effect of sorafenib on hepatocarcinogenesis.

scholarly journals Persistent effect of mTOR inhibition on preneoplastic foci progression and gene expression in a rat model of hepatocellular carcinoma

2016 ◽  
Vol 37 (4) ◽  
pp. 408-419 ◽  
Author(s):  
Heather Francois-Vaughan ◽  
Adeola O. Adebayo ◽  
Kate E. Brilliant ◽  
Nicola M.A. Parry ◽  
Philip A. Gruppuso ◽  
...  
Keyword(s):  
Gene Expression ◽  
Hepatocellular Carcinoma ◽  
Rat Model ◽  
Mtor Inhibition ◽  
Persistent Effect ◽  
Preneoplastic Foci

Abstract B55: mTOR signaling is critical to the development and expansion of preneoplastic foci in a rodent model of progenitor-marker positive hepatocellular carcinoma

2015 ◽  
Author(s):  
Heather Francois-Vaughan ◽  
Kate Brilliant ◽  
Adeola O. Adebayo ◽  
Nicola M.A. Parry ◽  
Philip A. Gruppuso ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Rodent Model ◽  
Mtor Signaling ◽  
Preneoplastic Foci

scholarly journals Preneoplastic foci in mice fed diethyl 1, 4-dihydro, 1, 4, 6-trimethyl 3, 5-pyridine decarboxylate are resistant to protoporphyrin accumulation

2015 ◽  
Vol 1 (2) ◽  
pp. 50
Author(s):  
SamuelW. French ◽  
M.Waheed Roomi
Keyword(s):  
Preneoplastic Foci

scholarly journals Helicobacter hepaticus Infection Promotes Hepatitis and Preneoplastic Foci in Farnesoid X Receptor (FXR) Deficient Mice

PLoS ONE ◽  
2014 ◽  
Vol 9 (9) ◽  
pp. e106764 ◽  
Author(s):  
Alton G. Swennes ◽  
Alexander Sheh ◽  
Nicola M. A. Parry ◽  
Sureshkumar Muthupalani ◽  
Kvin Lertpiriyapong ◽  
...  
Keyword(s):  
Farnesoid X Receptor ◽  
Helicobacter Hepaticus ◽  
Preneoplastic Foci ◽  
Deficient Mice

scholarly journals The inhibitory effect of rapamycin on the oval cell response and development of preneoplastic foci in the rat

2012 ◽  
Vol 93 (1) ◽  
pp. 40-49 ◽  
Author(s):  
Jennifer A. Sanders ◽  
Kate E. Brilliant ◽  
Danielle Clift ◽  
Ajay Patel ◽  
Bruno Cerretti ◽  
...  
Keyword(s):  
Cell Response ◽  
Inhibitory Effect ◽  
Oval Cell ◽  
Preneoplastic Foci

Induction of Liver Preneoplastic Foci in F344 Rats Subjected to 28-Day Oral Administration of Diheptyl Phthalate and Its In-Vivo Genotoxic Potential

2009 ◽  
Vol 141 (4) ◽  
pp. 299
Author(s):  
M. Jin ◽  
M. Kawi ◽  
Y. Saegusa ◽  
S. Matsumoto ◽  
M. Shibutani ◽  
...  
Keyword(s):  
Oral Administration ◽  
Genotoxic Potential ◽  
Preneoplastic Foci ◽  
F344 Rats

Induction of liver preneoplastic foci in F344 rats subjected to 28-day oral administration of diheptyl phthalate and its in vivo genotoxic potential

Toxicology ◽  
2009 ◽  
Vol 264 (1-2) ◽  
pp. 16-25 ◽  
Author(s):  
Meilan Jin ◽  
Yasuaki Dewa ◽  
Masaomi Kawai ◽  
Jihei Nishimura ◽  
Yukie Saegusa ◽  
...  
Keyword(s):  
Oral Administration ◽  
Genotoxic Potential ◽  
Preneoplastic Foci ◽  
F344 Rats
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