The effect of hypoxia on the surfactant system of the lungs

The study was conducted on mongrel male rats 120-180 g. Physical activity was performed by swimming for 40 minutes for 3 consecutive days. After three days, the development of insufficiency of the surfactant respiratory system was established, which will be characterized by moderate destruction of alveolocytes, violation of the entire aerogematic barrier as a whole, edema of alveolocytes, and, of course, POL. Key words: surfactant system of the lungs, physical activity, lipid peroxidation, respiratory organs.

Étude potentiométrique de la stabilité de complexes tensioactif–β-cyclodextrine

The complexation constants K of β-cyclodextrine with 13 ammonium surfactants were determined by a potentiometric method using electrodes selective to amphiphilic ions. Especially for C12, C14, and C16 tails, a model that provides for the formation of a second complex (β-CD)2M+, with a K1/K2 ratio of about 600, provides a good fit with the experimental curves. Results show a poor influence of the polar group, for example in the case of the dodecyl chain. On the other hand, the pK1 values and the hydrophobic tail length are linked by a linear relation up to n = 12 carbon atoms; beyond, pK1 tends to be proportionally smaller and pK2 more important. Key words: surfactant, β-cyclodextrin, selective electrodes, complexation constants, potentiometric study.