Extended Life
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2021 ◽  
Vol 13 (18) ◽  
pp. 10152
Author(s):  
Jianfeng Wu ◽  
Chuchu Jin ◽  
Lekai Zhang ◽  
Li Zhang ◽  
Ming Li ◽  
...  

Emotionally sustainable design helps users to develop an emotional attachment to a product and motivates them to continue using it, thus extending the product lifecycle, minimizing the need for new products and achieving product sustainability. However, the existing relevant design principles are still very scattered, and they could not effectively guide the emotionally sustainable design practice in a systematic way. We proposed an emotionally sustainable design (ESD) toolbox for product design based on the literature review and expert argumentation. The toolbox consists of seven themes and 20 principles under the three levels of emotional design. The usability of the ESD toolbox was then validated through design practice for the teapot product. The result shows that the ESD toolbox improved the efficiency of the sustainable design process and was helpful to the product’s sustainability.


Author(s):  
Manjesh B C

Abstract: The worldwide growth in call for refrigeration brought about the manufacturing of extra power and this, in turn, brought about extra use of CFCs. CFCs, in particular, are a notable factor in the ozone layer's depletion. TER (Thermoelectric Refrigerator) is a revolutionary option that eliminates the use of refrigerant. As a result, it is critical, especially in underdeveloped countries where extended life and inexpensive maintenance are required. The goal of this research is to design and build a functional TER that uses the Peltier effect to cool this volume to much lower temperature in under two hours and retain it for at least the next 1/2 hour. In this project, we created a TE system that works with both solar and electrical power. Food preservation, military or aerospace equipment, medicinal and pharmaceutical equipment are just some of the uses for the project. Keywords: Thermo-electric Refrigerator, CFCs, COP, Peltier Effect


2021 ◽  
Author(s):  
Dhyanjyoti Deka ◽  
Mike Campbell ◽  
Vinayak Patil ◽  
Michael Long Ge ◽  
Steve Wong ◽  
...  

Abstract The Tensioned Riser Assessment for Continued Service (TRACS) JIP develops a structured life extension process for TTR systems including single casing, dual casing, buoyancy can supported and tensioner supported TTRs. The JIP bridges regulatory and API frameworks and achieves industry consensus on analysis, inspections, and documentation. The life extension process developed in this JIP consists of detailed roadmaps that guide the operator through the different assessment steps starting from initial data gathering through to the development of the forward-looking IMP. The JIP life extension process is based on a threat assessment philosophy which ensures identification and assessment of all possible threats to the integrity of the TTR in its extended life. The JIP process is validated against three real life TTR systems that are nearing the end of their design lives. Potential threats to the integrity of these TTRs during the projected continued service beyond the design life are identified and specific inspection and analysis recommendations to safely manage or mitigate these threats are made. The JIP also provides TTR life extension analysis guidance while considering the opportunities to reduce conservatism compared to new designs. Inspection of TTRs is challenging due to accessibility issues and the pipe in pipe construction. Several subsea NDE inspection tools are surveyed in this JIP and their applicability to TTRs is discussed.


Science ◽  
2021 ◽  
Vol 373 (6554) ◽  
pp. eabc8479
Author(s):  
M. Grunewald ◽  
S. Kumar ◽  
H. Sharife ◽  
E. Volinsky ◽  
A. Gileles-Hillel ◽  
...  

Aging is an established risk factor for vascular diseases, but vascular aging itself may contribute to the progressive deterioration of organ function. Here, we show in aged mice that vascular endothelial growth factor (VEGF) signaling insufficiency, which is caused by increased production of decoy receptors, may drive physiological aging across multiple organ systems. Increasing VEGF signaling prevented age-associated capillary loss, improved organ perfusion and function, and extended life span. Healthier aging was evidenced by favorable metabolism and body composition and amelioration of aging-associated pathologies including hepatic steatosis, sarcopenia, osteoporosis, “inflammaging” (age-related multiorgan chronic inflammation), and increased tumor burden. These results indicate that VEGF signaling insufficiency affects organ aging in mice and suggest that modulating this pathway may result in increased mammalian life span and improved overall health.


Author(s):  
Hamed Hajebzadeh ◽  
Abdulhamid NM Ansari

The main goal of this study is to achieve the extended operating life of the rotary regenerative air pre-heater (Ljungström) of Bandar Abbas power plant by modifying operational parameters by decreasing the corrosion. To achieve this goal, a three-dimensional CFD simulation of the Ljungström is carried out, utilizing the thermal non-equilibrium porous media model. Temperatures are validated against measured data from the power plant with a maximum relative error of 5.54% on the Celsius scale, and mass flow rates are validated with a maximum relative error of −5.25%. The effect of the Ljungström key parameters including the rotational speed, cold layer material, inlet air/flue gas temperature, and mass flow rate, are analyzed in presence of leakages and neglecting it, using porous media approach. The leakage effect is investigated considering radial and axial/peripheral clearances. Finally, a simulation is performed by applying feasible improved parameters extracted from the above analyses considering the effect of all parameters together in presence of leakages, which shows a 6.14% improvement in the Ljungström effectiveness, reducing the total leakage to about one-third of the actual model and eliminating any corrosion.


2021 ◽  
Vol 22 (14) ◽  
pp. 7544
Author(s):  
Masatoshi Kitakaze ◽  
Ryota Chijimatsu ◽  
Andrea Vecchione ◽  
Toru Kitagawa ◽  
Yuichiro Doki ◽  
...  

The recent advances in deciphering the human genome allow us to understand and evaluate the mechanisms of human genome age-associated transformations, which are largely unclear. Genome sequencing techniques assure comprehensive mapping of human genetics; however, understanding of gene functional interactions, specifically of time/age-dependent modifications, remain challenging. The age of the genome is defined by the sum of individual (inherited) and acquired genomic traits, based on internal and external factors that impact ontogenesis from the moment of egg fertilization and embryonic development. The biological part of genomic age opens a new perspective for intervention. The discovery of single cell-based mechanisms for genetic change indicates the possibility of influencing aging and associated disease burden, as well as metabolism. Cell populations with transformed genetic background were shown to serve as the origin of common diseases during extended life expectancy (superaging). Consequently, age-related cell transformation leads to cancer and cell degeneration (senescence). This article aims to describe current advances in the genomic mechanisms of senescence and its role in the spatiotemporal spread of epithelial clones and cell evolution.


2021 ◽  
Vol 7 (3) ◽  
Author(s):  
Nagoor Basha Shaik ◽  
Kedar Mallik Mantrala ◽  
Balaji Bakthavatchalam ◽  
Qandeel Fatima Gillani ◽  
M. Faisal Rehman ◽  
...  

AbstractThe well-known fact of metallurgy is that the lifetime of a metal structure depends on the material's corrosion rate. Therefore, applying an appropriate prediction of corrosion process for the manufactured metals or alloys trigger an extended life of the product. At present, the current prediction models for additive manufactured alloys are either complicated or built on a restricted basis towards corrosion depletion. This paper presents a novel approach to estimate the corrosion rate and corrosion potential prediction by considering significant major parameters such as solution time, aging time, aging temperature, and corrosion test time. The Laser Engineered Net Shaping (LENS), which is an additive manufacturing process used in the manufacturing of health care equipment, was investigated in the present research. All the accumulated information used to manufacture the LENS-based Cobalt-Chromium-Molybdenum (CoCrMo) alloy was considered from previous literature. They enabled to create a robust Bayesian Regularization (BR)-based Artificial Neural Network (ANN) in order to predict with accuracy the material best corrosion properties. The achieved data were validated by investigating its experimental behavior. It was found a very good agreement between the predicted values generated with the BRANN model and experimental values. The robustness of the proposed approach allows to implement the manufactured materials successfully in the biomedical implants.


Author(s):  
Shrutirekha Tripathy ◽  
Mitali M. Sahoo ◽  
Nimay Chandra Giri ◽  
Siba Prasad Mishra ◽  
Smruti Ranjan Nayak

About 200 million people of India are deprived of grid based power supply, prominently in inaccessible hilly and rural hamlets of the country. Present research is an attempt to design, install, operate use, and maintain the hand on set of light source to address the unserved populations dwelling in electricity inaccessible areas in India. The approach is designing and developing a low cost sustainable or solar emergency light through, “Solar Home Lighting Systems” or “Sustainable Emergency Light” technology, which is one of the smart and innovative approaches of illuminating sources by harnessing solar energy to light the darkened places. The attractive daily usable gadget with surged luminous efficiency, durability, extended life, ecofriendly, compact, and efficient to work at both small values of current and voltages and they are growing acceptance. The safe and non-ignition start, is the uniqueness over conventional emergency light, and solar energy founded. The stand-alone device with mobile charging port with luminosity of 150 Lux can be used in lighting the escape routes, open areas and high risk areas. Under the crisis of pandemic of Covid-19 virus, the portable solar lights is  safe and riskless light source for the economic backward classes, and can provide the children and students for online undisrupted  study up to about 8 to 10 hours at low cost in remote areas.


Author(s):  
S. I. Romanov ◽  
O. A. Botvinova ◽  
E. A. Timakov ◽  
L. A. Chizhova ◽  
Yu. T. Panov

Objectives. Improvement of the technology for obtaining polymer-sprayed coatings based on polycarbodiimides (polyureas) with high chemical, hydrolytic, and abrasive resistance and improved physical and mechanical properties, as well as obtainment of polyurea compositions with a lifetime of at least 5 min without loss performance characteristics (i.e., “hand-applied” polyureas) suitable for repair of coatings already in use.Methods. The reaction rate between isocyanate and amino groups is almost a hundred times higher than that between isocyanate and hydroxyl groups, necessitating the use of special highperformance and high-pressure installations equipped with self-cleaning mixing chambers and heating of components. The following are determined from the obtained materials: strength, elongation at break according to the standard method, Taber abrasion, and Shore hardness.Results. Three methods of slowing down the reaction are investigated: 1) the synthesis of prepolymers with the content of NCO groups from 10.5% to 18%; 2) the addition of a plasticizer into the prepolymer in the amount of 1–10 mass parts; and 3) the introduction of polyesters into the composition and radiation of the so-called “hybrid” systems. When using 14% polyesters with a molecular weight of 2000 Da, only “hybrid” systems make it possible to obtain compositions with a lifetime of more than 5 min. At the same time, the tensile strength decreases by 20%, and the abrasion increases by 40%; however, such “hybrid” systems have a higher adhesion force and are cheaper than pure polyureas, allowing them to be used as “repair” systems.Conclusions. The developed composition and technology of applying “hybrid” systems allow for the repair of existing coatings without using specialized devices. “Manual” polyurea is easy to use and does not require special training. 


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