Human infection with pandemic Influenza (H1N1): A Review Article

Swine flu, also known as the H1N1 virus, is new strain of an influenza virus that causes symptoms similar to the regular flu. It originated in pigs, but is spread rapidly from person to person. Therefore, the objectives of this article are to highlight on H1N1 Influenza, its mode of transmission, risk factor, clinical spectrums and preventive ways. Studies published relevant to swine flu was searched through scientific databases like MEDLINE, Pubmed and online search engines like ‘Google Scholar’. Eligible studies involved at least one factor related to ‘influenza A virus’, ‘H1N1 subtype’, ‘epidemiology’, ‘transmission” and ‘preventive measures’ etc. Searches were limited to human only and also looked at the websites of the leading health authorities (e.g. WHO, CDC, HPA). Swine is a new flu virus that appears in human and spreads very quickly from person to person. In Nepal, the first case was detected on June 2009 after that the case is increasing day by day. In 2010 till May there were 172 confirmed positive cases, likewise on August 7, 2017 there were 10 death and 354 positive cases of swine flu in Nepal. Therefore, Government of Nepal has broadcasted awareness programs, organized seminars and meetings, to make people aware regarding H1N1 Influenza. But, it seems challenging to decrease its outbreak in Nepal because of low financial resources, low manpower, limited technology and political instability.

Outcome of suspected H1N1 influenza cases admitted in tertiary care Govt. Hospital Solapur, Maharashtra

<span class="ABS_Bold-Italic" lang="en-GB">Introduction:</span><span> Influenza (H1N1) is very sensitive and newly emerged pandemic. Influenza (H1N1) pandemics are caused by new influenza viruses that have recently adapted to humans and resemble major natural disasters both in terms of recurrence and magnitude. </span><span class="ABS_Bold-Italic" lang="en-GB">Aims and Objectives:</span><span> To study the outcome and epidemiological factors of suspected H1N1 influenza cases. </span><span class="ABS_Bold-Italic" lang="en-GB">Study Design:</span><span> Hospital-based descriptive study, </span><span class="ABS_Bold-Italic" lang="en-GB">Study Period:</span><span> Study was conducted over a period of seven months from April 2009 to October 2009. </span><span class="ABS_Bold-Italic" lang="en-GB">Study Variable:</span><span> Outcome, age, sex, time, place of residence. </span><span class="ABS_Bold-Italic" lang="en-GB">Results and Discussion:</span><span> The total 110 cases of suspected H1N1 influenza were admitted in Infectious diseases ward of Government Hospital Solapur. Out of 110 total suspected cases, 91 (82.72%) were cured and discharged. Among these 91 (82.72%) suspected cases, 17 (15.45%) were laboratory confirmed for Influenza (H1N1). </span><span class="ABS_Bold-Italic" lang="en-GB">Conclusion:</span><span> In present study, maximum case fatality rate (32%) was observed in females in age group of 15-44 years as compared to male.</span>