Toscana virus encephalitis in Southwest Germany: a retrospective study

Background Toscana virus (TOSV) is an arthropod-borne virus transmitted by phlebotomine sandflies (Phlebotomus sp.) widespread throughout the Mediterranean having the potential to cause meningoencephalitis in humans. In Germany, the vectors of TOSV are introduced recently and become endemic especially in Southwestern Germany. As TOSV is not investigated regularly in patients with meningoencephalitis, cases of TOSV-neuroinvasive disease may remain mostly undetected. Methods We conducted a retrospective cohort study on patients with meningoencephalitis without identification of a causal pathogen from 2006 to 2016. Serologic assessment for anti-TOSV-IgG and IgM was performed on serum and CSF. Demographic, clinical and CSF data from TOSV-positive patients were compared to a cohort of patients with meningoencephalitis due to enterovirus. Informed consent was obtained from all included patients. Results We found 138 patients with meningoencephalitis without identified causal pathogen. From 98 of these patients CSF and serum was available for further testing. Additionally, we included 27 patients with meningoencephalitis due to enterovirus. We identified two patients with serological confirmed TOSV-neuroinvasive disease (TOSV-IgM and IgG positive, 2%) and two patients with possible TOSV-neuroinvasive disease (isolated TOSV-IgM positive, 2%). Overall, TOSV-neuroinvasive was detected in 4% of our cases with suspected viral meningoencephalitis. None of them had a history of recent travel to an endemic area. Conclusions We found cases of TOSV-neuroinvasive disease in our German cohort of patients with meningoencephalitis. As no recent history of travel to an endemic area was reported, it remains probable that these cases resemble autochthonous infections, albeit we cannot draw conclusions regarding the origin of the respective vectors. TOSV could be considered in patients with meningoencephalitis in Germany.

Cydalima perspectalis (box tree moth).

The box tree moth, Cydalima perspectalis, is native to East Asia (Inoue et al., 1982). It was first recorded in Europe in 2007, in southwest Germany and the Netherlands (Krüger, 2008; Straten and Muus, 2010). Since then it has been recorded in many other European countries, and climate models predict further spread of the species in Europe, invading most areas except for Northern Fenno-Scandinavia, Northern Scotland and high mountain regions (Nacambo et al., 2014). In the newly invaded regions, C. perspectalis larvae feed on the leaves of box trees, Buxus spp., resulting in defoliation, which can kill the trees. The most significant damage, however, can be from the larvae attacking the bark of box trees causing the trees to dry out and die. Besides cultural and economic effects, the most serious threat from C. perspectalis is on the natural Buxus populations (Kenis et al., 2013). The species is easily introduced accidentally with its host plant, which is extensively traded over Europe and therefore presents a serious threat (Leuthardt et al., 2010; Straten and Muus, 2010).

Calcerous Tufa as Invaluable Geotopes Endangered by (Over-)Tourism: A Case Study in the UNESCO Global Geopark Swabian Alb, Germany

Calcerous tufa and sinter are among the most impressive natural spectacles in karst landscapes whose scientific and aesthetic value is universally recognized. Being visually often very appealing they attract numerous visitors. At the same time tufa landforms are extremely vulnerable and can be seriously damaged even by minor interference. The challenge is, therefore, to protect the calcerous tufa heritage, to communicate its values, and to enhance it with the help of adequate geotourism offers. Tufa geotopes are an essential part of the geological heritage of the UNESCO Global Geopark Swabian Alb in Southwest Germany. Unfortunately tufa landforms, especially tufa cascades, suffer serious impairments by (over-)tourism, particularly during the Corona pandemic. The article explores where best to strike the balance between valorization and protection, as well as how to ensure that growth in tourism is compatible with nature preservation, especially in the case of the extremely vulnerable tufa geotopes.

The Meaning of Imagined Pilgrimage

There is growing interest among historians of late medieval and early modern Europe in the concept of resistance for understanding women and power. Researchers are beginning to look beyond religious women’s overt and well-documented forms of opposition to reform efforts that increasingly restricted their physical enclosure; they contend that these women also resisted through more subtle cultural means, such as the devotional practice of imagined pilgrimage. Yet recent studies — including one by this author — have argued unconvincingly that late medieval Dominican nuns in southwest Germany who took mental journeys to Jerusalem or Rome thereby resisted their enclosure. This article uses an approach created by the anthropologist Sherry Ortner to check and correct this resistance model. It shows that the interpretation of what imagined pilgrimage meant to and for these late medieval women is most likely an effect of scholars’ present biases, both intellectual and sociocultural.