Laparoscopic Live Donor Nephrectomy: Experience of High-Volume Center with 2,477 Cases

<b><i>Objective:</i></b> Donors’ health and safety are mandatory in the living-donor kidney transplantation procedure. Laparoscopic live donor nephrectomy (LLDN) provides an increase in donor numbers with its benefits and becomes a standard of care. We aimed to explain the results, complication rates, tips, and tricks of the largest number of LLDN case series ever performed in the literature. <b><i>Materials and Methods:</i></b> Between August 2012 and December 2019, 2,477 live donor case files were analyzed retrospectively. Age, gender, hospitalization times, body mass index, warm ischemia times, operation times, numbers of arteries, side of the kidneys, and complications were noted. <b><i>Results:</i></b> 1,421 (57.4%) of 2,477 donors were female (<i>p</i> = 0.007). Operation times and warm ischemia times were found longer in right-sided LLDN and donors with multiple renal arteries (<i>p</i> = 0.046, &#x3c;0.001, and &#x3c;0.001, respectively). Obesity (BMI &#x3e;30 kg/m²) did not affect warm ischemia times while prolonging the operation times (<i>p</i> = 0.013). Hospitalization times and numbers of complications were higher in obese donors. <b><i>Conclusions:</i></b> LLDN seems to be a reliable solution with fewer complications and higher satisfaction rates. We hope to illuminate the way with tips and trick points for beginner transplant surgeons based on the experience obtained from 2,477 LLDN cases.