OPTICAL COHERENCE TOMOGRAPHY;

ABSTRACT: PURPOSE: To study the changes in Ganglion Cell Complex as measured on OCT after phacoemulsification with intra ocular lens implantation. STUDY DESIGN: Quasi experimental study PLACE AND DURATION OF STUDY: Department of Ophthalmology, Lahore General Hospital, Lahore from 1-3-2017 to 30-4-2018 MATERIALS AND METHODS: Ethical approval of the study was obtained from ‘’Ethical Review Committee’’ of Lahore General Hospital, Lahore. Patients presenting to the Eye OPD Lahore General Hospital were assessed for inclusion and exclusion criteria. All patients (n=64) diagnosed with cataract requiring surgery were included in study. Patients having any coexisting ocular pathology hindering the OCT measurement i.e. Corneal opacity, Vitreous hemorrhage, Retinal detachment were excluded from study. Retinal Ganglion Cell Complex thickness was measured in Superior, Inferior, Supero-Nasal, Supero-Temporal, Infero-Nasal and Infero-Temporal quadrants. Besides that Signal Strength on OCT was also documented. Pre-Operatively, Visual acuity was measured and OCT performed and the findings were recorded on a designed proforma. Post-Operatively, the patients were called for follow-up after one month at which time Visual acuity was again measured and OCT performed and findings recorded in the proforma. All the surgeries were performed by single surgeon. RESULTS: The thickness of Ganglion Cell Complex increased significantly (p<0.001) one month after cataract surgery. CONCLUSION: Cataract surgery does affect the measurement of Retinal Ganglion Cell Complex thickness on OCT.