grass pollen counts
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2021 ◽  
Vol 2 ◽  
Author(s):  
Letty A. de Weger ◽  
Peter Th. W. van Hal ◽  
Bernadette Bos ◽  
Frank Molster ◽  
Marijke Mostert ◽  
...  

Background: Pollen is a major trigger for allergic symptoms in sensitized individuals. Airborne pollen is usually monitored by Hirst type pollen samplers located at rooftop level, providing a general overview of the pollen distribution in the larger surroundings. In this feasibility study, grass pollen-sensitized subjects monitored the pollen in their direct environment using a portable pollen sampler (Pollensniffer) and scored their symptoms, to study the relation between symptom severity and personal grass pollen exposure. For comparison the symptoms were also correlated with pollen collected by the rooftop sampler.Methods: After recruitment 18 participants were screened for grass pollen specific (GP-sIgE) of which 12 were eligible. Nine participants completed the study (May, 2018). They were asked to monitor personal pollen exposure using a Pollensniffer on their way to school, work or other destination, and to score their symptoms via a mobile app on a scale from 0 to 10. Daily pollen concentrations were collected by a Hirst type sampler at rooftop level. Pollen grains were analyzed using a microscope.Results: Three of the four participants with high GP-sIgE (≥9.6 kU/l) reported high symptom scores (>4) and an analysis showed a significant correlation (CC) between eye, nose, and lung symptoms and the grass pollen counts collected by the Pollensniffer, as well as the daily grass pollen concentrations monitored by the rooftop sampler (CC≥0.54). In contrast, the participants with low GP-sIgE levels (<9.6 kU/l) reported low symptom scores (≤4) and often other sensitizations were present. For these subjects, no significant positive correlations (CC<0.3) of symptoms with either grass pollen collected by the personal or the rooftop sampler were found.Conclusion: The results of this feasibility study suggest that correlations between the severity of clinical symptoms of grass pollen allergic patients, and grass pollen counts as determined by the Pollensniffer or a rooftop sampler, is restricted to patients with high GP-sIgE levels, high symptom scores, and no relevant other sensitizations. Based on the low numbers of subjects with severe symptoms included in this feasibility study, no conclusions can be drawn on the performance of the Pollensniffer in relating symptoms and pollen exposure in comparison with the rooftop sampler.Trial Registration: The study was approved by the Committee Medical Ethics of the LUMC (approval numbers: NL63953.058.17/ P17.304).



2020 ◽  
Author(s):  
Letty de Weger ◽  
Peter TH.W van Hal ◽  
Bernadette Bos ◽  
Frank Molster ◽  
Marijke Mostert ◽  
...  

Abstract Background. Pollen is a major trigger for allergic symptoms in sensitized individuals. Airborne pollen is usually monitored by Hirst type pollen samplers located at rooftop level, providing a general overview of the pollen distribution in the larger surroundings. In this feasibility study, grass pollen-sensitized subjects monitored the pollen in their direct environment using a portable pollen sampler (Pollensniffer) and scored their symptoms, to study the relation between symptom severity and personal grass pollen exposure. For comparison the symptoms were also correlated with pollen collected by the rooftop sampler. Methods. Nine grass pollen-sensitized individuals were enrolled in this study (May 2018) and asked to monitor personal pollen exposure using a Pollensniffer on their way to school, work or other destination, and to score their symptoms via a mobile app on a scale from 0 to 10. Daily pollen concentrations were collected by a Hirst type sampler at rooftop level. Pollen grains were analysed using a microscope. Results. Three of the four participants with high grass pollen-specific (GPS) IgE (>9.6 kU/l) reported high symptom scores (>4) and an analysis showed a significant correlation (CC) between eye, nose and lung symptoms and the grass pollen counts collected by the Pollensniffer, as well as the daily grass pollen concentrations monitored by the rooftop sampler (CC>0.54). In contrast, the participants with low GPS IgE levels (<9.6 kU/l) reported low symptom scores (<4) and often other sensitizations were present. For these subjects, no significant positive correlations (CC<0.3) of symptoms with either grass pollen collected by the personal or the rooftop sampler were found. Conclusion. Our results show that correlations between the severity of clinical symptoms of grass pollen allergic patients, and airborne grass pollen counts as determined by a personal pollen sampler (Pollensniffer) or a rooftop sampler, is restricted to patients with high GPS IgE levels, high symptom scores and no relevant other sensitizations. Based on the number of subjects included in this feasibility study, no conclusions can be drawn on the performance of the personal pollen sampler in relating symptoms and pollen exposure in comparison with the rooftop sampler.Trial registrationThe study was approved by the Committee Medical Ethics of the LUMC (approval numbers: NL63953.058.17/ P17.304).



2018 ◽  
Vol 2018 (1) ◽  
Author(s):  
Ha Thanh Nguyen ◽  
Xuanlong Ma ◽  
Ed Newbigin ◽  
Paul Beggs ◽  
Janet Davies ◽  
...  


2016 ◽  
Vol 77 (09) ◽  
pp. 1160-1167 ◽  
Author(s):  
Haekyung Jeon-Slaughter ◽  
Cynthia A. Claassen ◽  
David A. Khan ◽  
Perry Mihalakos ◽  
Kevin B. Lee ◽  
...  


2016 ◽  
Vol 137 (2) ◽  
pp. AB122
Author(s):  
Fabian M. Ramon ◽  
Nadia Arango ◽  
Laura B. Barrionuevo ◽  
Adrian M. Kahn ◽  
Julieta Ribas ◽  
...  


PEDIATRICS ◽  
2013 ◽  
Vol 132 (Supplement) ◽  
pp. S29-S29 ◽  
Author(s):  
D. A. Andreae ◽  
J. Wang


2012 ◽  
Vol 158 (4) ◽  
pp. 397-404 ◽  
Author(s):  
Isabella Annesi-Maesano ◽  
Sarah Rouve ◽  
Hélène Desqueyroux ◽  
Roger Jankovski ◽  
Jean-Michel Klossek ◽  
...  


Aerobiologia ◽  
2009 ◽  
Vol 25 (4) ◽  
pp. 321-332 ◽  
Author(s):  
Matt Smith ◽  
Jean Emberlin ◽  
Alicja Stach ◽  
Auli Rantio-Lehtimäki ◽  
Eric Caulton ◽  
...  


2003 ◽  
Vol 82 (8) ◽  
pp. 592-597 ◽  
Author(s):  
Cetin Vural ◽  
Anil Gungor

Nitric oxide (NO) in exhaled breath is produced primarily by the upper respiratory airway mucosa. The nasal output of this gas is increased in patients with allergic rhinitis. We performed a study on a 41 -year-old nonsmoking male volunteer with allergic rhinitis to investigate the effect of fluticasone nasal spray on nasal NO output (VNO). A total of 28 nasal NO measurements from both nostrils were taken during the 2-month period of June and July 2002. During the second half of the study period (treatment phase), the patient took fluticasone in doses of 100 μg per nostril once a day. During the treatment phase, nasal NO measurements were taken 10 days after the initiation of treatment. In addition, we also recorded the patient's nasal symptom scores and the grass pollen counts in the greater Pittsburgh area. The patient's mean VNO was 989.9 nl/min prior to treatment and 787.7 nl/min following treatment—a statistically significant 20.4% decrease (p<0.01) The findings of our study support the observation that topical nasal steroid treatment decreases NO production in sinonasal mucosa.



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