AbstractThroughout its history, Benemérita Universidad Autónoma de Puebla (BUAP), a public institution, has always been a guide of social and economic development of the state of Puebla. From one moment to another, the state was unexpectedly immersed in the Covid-19 pandemic that caused the sudden migration from a mostly face-to-face instructional model to an online one. Immediately, the institution summoned different staff members to define and analyze the situation and then establish actions to guarantee educational continuity.As part of this analysis, they identified opportunities specifically at the upper secondary level, which includes high school. In particular, one opportunity was to offer entrepreneurship courses in an online format, capitalizing on the experience gained from the undergraduate program. Given the characteristics of the pandemic, the analysis also highlighted that the crisis would have severe economic effects on the students and their families, diminishing their income.It is estimated that the entrepreneurship education program reached 18,000 people, including students, faculty members, and parents. Over 10,000 more people will be reached throughout the rest of the year. Therefore, it is essential to strengthen the resilience, innovation, and entrepreneurial capacity of the university ecosystem.