ocular implant
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PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0242274
Author(s):  
So-Young Park ◽  
Jeong-Hee An ◽  
Hyun Kwon ◽  
Seo-Young Choi ◽  
Ka-Young Lim ◽  
...  

Various incurable eye diseases in companion animals often result in phthisis bulbi and eye removal surgery. Currently, the evisceration method using silicone balls is useful in animals; however, it is not available to those with impaired cornea or severe ocular atrophy. Moreover, ocular implant and prostheses are not widely used because of the diversity in animal size and eye shape, and high manufacturing cost. Here, we produced low-cost and customized artificial eyes, including implant and prosthesis, using computer-aided design and three-dimensional (3D) printing technique. For 3D modeling, the size of the artificial eyes was optimized using B-mode ultrasonography. The design was exported to STL files, and then printed using polycaprolactone (PCL) for prosthesis and mixture of PCL and hydroxyapatite (HA) for ocular implant. The 3D printed artificial eyes could be produced in less than one and half hour. The prosthesis was painted using oil colors and biocompatible resin. Two types of eye removal surgery, including evisceration and enucleation, were performed using two beagle dogs, as a preliminary study. After the surgery, the dogs were clinically evaluated for 6 months and then histopathological evaluation of the implant was done. Ocular implant was biocompatible and host tissue ingrowth was induced after in vivo application. The custom-made prosthesis was cosmetically excellent. Although long-term clinical follow-up might be required, the use of 3D printed-customized artificial eyes may be beneficial for animals that need personalized artificial eye surgery.


2018 ◽  
Vol 157 ◽  
pp. 100-106
Author(s):  
Abeer H.A. Mohamed-Ahmed ◽  
Alastair Lockwood ◽  
Hala Fadda ◽  
Shivam Madaan ◽  
Peng T. Khaw ◽  
...  
Keyword(s):  

2018 ◽  
Vol 106 (8) ◽  
pp. 2261-2271 ◽  
Author(s):  
Parisa Badiee ◽  
Reyhaneh Varshochian ◽  
Morteza Rafiee-Tehrani ◽  
Farid Abedin Dorkoosh ◽  
Mohammad Reza Khoshayand ◽  
...  

2015 ◽  
Vol 5 (5) ◽  
pp. 469-479 ◽  
Author(s):  
Xu Wen Ng ◽  
Kerh Lin Liu ◽  
Amutha Barathi Veluchamy ◽  
Nyein Chan Lwin ◽  
Tina T. Wong ◽  
...  

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