A rare but serious complication of cholecystolithiasis is the transition of a gallstone in the gastrointestinal tract through a biliary-enteric fistula, thereby causing a traffic mechanical obstruction of intestine. We report a case of cholecysto-duodenal fistula that causes small bowel obstruction by gallstone (gallstone ileus). A 35-year-old male patient with a history of type 1 diabetes and stroke sequelae, clinical presentation of intestinal obstruction with abdominal pain, vomiting, does not fart and defecate, abdominal distention. Multi-slice computer tomography scan of the abdomen shows large dilated small bowel loops containing airfluid levels, colon is in normal aspect, detects foreign body that is spherical and high density like target shape in the distal ileum loop at the right iliac fossa. Result of surgery is a big bile stone with 30mm in diameter located in the ileum loop.