Notes on the Malachiini of the East-Mediterranean region, with description of a new species (Coleoptera, Melyridae, Malachiinae)

New distributional data are here presented for the genera Clanoptilus Motschulsky 1854 and Malachius Fabricius 1775 in the East-Mediterranean region. Malachius saltinii n.sp. is described from Lebanon.

Phenotypes and natural history of food protein‐induced enterocolitis syndrome in the east Mediterranean region

Background: Food protein‐induced enterocolitis syndrome (FPIES) is a rare non-IgE mediated food allergy. Objective: To delineate the differences in the spectrum of culprit foods, remission patterns, and predictors among varying cultures. Methods: We reviewed demographics, culprit foods, outcomes, and predictors in 81 children with a diagnosis of FPIES who were followed up between 2015 and 2020. Results: Eighty-one patients (55.6% boys) were enrolled, including 72 with acute FPIES and 9 with chronic FPIES. Hen’s egg was the most common culprit food (36.6%), followed by fish (26.9%), and cow’s milk (21.5%). Interestingly, cow’s milk was significantly prevalent in chronic FPIES cases (p = 0.006). The most common clinical symptoms were vomiting (100%), pallor (63.4%), and lethargy (55.9%). Emergency department visits were noted in 39 patients (41.9%), of whom 37 (39.8%) were treated with intravenous (IV) fluid. The subjects were followed up for a median (interquartile range) of 19.4 months (12.3‐41.2 months), and 26 subjects (32.1%) achieved tolerance. The median (interquartile range) age at tolerance was 2.5 years (2.1‐3.2 years). With regard to the culprit foods, hen’s egg was observed more frequently in the subjects with resolved FPIES cases (p = 0.008), whereas fish FPIES cases were high in the persistent group (p = 0.001). IgE sensitization of the culprit food was found to be an independent risk factor for the persistence of FPIES (odds ratio 4.855 [95% confidence interval, 1.131‐20.844]; p = 0.034). Conclusion: In our cohort, unlike other published series, hen’s egg and fish were the two most common culprit foods. Fish differed from other culprit foods, with significantly delayed onset and persistence, and may create a model that allows for the understanding of the disease.

Entomological Survey for the Detection of Sand Fly Fauna and Vector Species in the Cutaneous Leishmaniasis Endemic Area in East Mediterranean Region of Turkey, Mersin Province

Cutaneous (CL) and visceral (VL) forms of leishmaniasis, transmitted by sand flies, are seen in all countries located in Mediterranean Basin including Turkey. In this study, we aimed to conduct an entomological survey for the detection of sand fly fauna and vector species in Mersin province, one of the important endemic areas for CL in Turkey. In total, 912 sand fly specimens were collected in 2010 and 2011 using CDC light traps. Nine Phlebotomus (Diptera: Psychodidae) and three Sergentomyia (Diptera: Psychodidae) species were detected. Of the collected Phlebotomus sand flies, P. sergenti Parrot, 1917 (30.1%) was the most dominant followed by P. alexandri Sinton, 1928 (18.2%), P. neglectus/syriacus Tonnoir Adler (12.0%), P. tobbi Adler & Theodor, 1930 (11.7%), and P. papatasi Scopoli, 1786 (10.2%), while S. minuta Rondani, 1843 (11.3%) was the dominant species among Sergentomyia. During the field work in 2011, female specimens (n = 81) were screened for the presence of Leishmania promastigotes by midgut dissection, and all were found negative. The rest of the collected female specimens (n = 334) were pooled according to species (P. alexandri, P. neglectus/syriacus, P. papatasi, P. sergenti, P. simici, and P. tobbi) and location (Mut, Silifke, and Anamur). In total, 29 pools were generated and real-time ITS1 PCR assay was performed to detect and identify natural Leishmania Ross, 1903 (Kinetoplastida: Trypanosomatida) infection. Two pools, both from Mut town, containing P. sergenti specimens were found positive and Leishmania tropica Ross, 1903 was identified as an infectious agent for both pools. In conclusion, the sand fly fauna was determined in an endemic area for CL. The detection of L. tropica DNA in P. sergenti specimens showed the possible vectorial role of this species in Mersin province.

Teaching with Images among the Jews and Manichaeans of Late Antique Mesopotamia

Although much has been written about the art of the famous synagogue at Dura-Europos, its rootedness in Mesopotamia has gone largely unexplored. This study looks south along the local trade routes to Iranian Babylonia and examines evidence available about the religious function of Durian Jewish and Sasanian Manichaean pictorial art as part of a shared regional development of techniques of instruction. It reveals that the distinctly different forms of pictorial art used by these two communities in mid-third-century Mesopotamia are nevertheless comparable based on their didactic function. They both: (1) displayed a visual library of doctrinal subjects, that is, they captured, in pictorial form, a large sample of core tenets which were also recorded in the respective sacred texts of these religions; (2) fulfilled a primarily didactic function, that is, their pictorial genres (narrative scenes, didactic portraits, and diagrams in the Manichaean case) played a dominantly instructional role; and (3) effectively supplemented oral instruction, that is, the paintings were sermonized about and discussed in light of living interpretations. I argue that these correlations result not from direct influence between the two communities, but rather from a shared approach to what images can do for a religion. The Jewish and Manichaean paintings in question emerged simultaneously and in relative closeness to one another. While the Jewish archeological records of the painted synagogue are all but silent, various characteristics of the mid-third-century Manichaean paintings are noted in literary records, including what they portrayed and, most importantly for this study, the pedagogical reasons for how and why they were used. As evidenced by Iranian, Coptic, and Syriac textual sources from between the mid-third and the late fourth and early fifth centuries, the founding prophet of Manichaeism, Mani (active from 240 to 274/277 CE), not only wrote down his own teachings, but also created visual representations of them on a solely pictorial scroll—the Book of Pictures—that he and his highest-ranking elects used in the course of oral instructions while missionizing across greater West Asia and the East Mediterranean region.