Thrombosis and kidney disease in cancer: comorbidities defining a very high risk patient: A position paper from the Cancer & the Kidney International Network

Cancer & the Kidney International Network was created in 2014. The aim was to improve the management of cancer patients by developing clinical and scientific knowledge on the main topic of cancer and the kidney. Therefore, the Cancer & the Kidney International Network created a special working group: the Thrombosis, Kidney Disease, and Cancer working Group. The first step of this force was to produce a position paper on this topic by investigating the association of chronic kidney disease and venous thromboembolism in cancer patients, focusing particularly on the anticoagulant management of patients presenting these three comorbidities. The use of low-molecular-weight heparins, vitamin K agonists and oral direct anticoagulants in cancer patients with chronic kidney disease was reviewed.

Mesh Convergence Studies for Thick Shell Elements Developed by the ASME Special Working Group on Computational Modeling

The ASME Special Working Group on Computational Modeling for Explicit Dynamics was founded in August 2008 for the purpose of creating a quantitative guidance document for the development of finite element models used to analyze energy-limited events using explicit dynamics software. This document will be referenced in the ASME Code Section III, Division 3 and the next revision of NRC Regulatory Guide 7.6 as a means by which the quality of a finite element model may be judged. One portion of the document will be devoted to a series of element convergence studies that can aid designers in establishing the mesh refinement requirements necessary to achieve accurate results for a variety of different element types in regions of high plastic strain. These convergence studies will also aid reviewers in evaluating the quality of a finite element model and the apparent accuracy of its results. In this paper, the authors present the results of a convergence study for an impulsively loaded propped cantilever beam constructed of LS-DYNA thick shell elements using both reduced and selectively reduced integration. A large load is applied to produce large deformations and large plastic strains in the beam. The deformation and plastic strain results are then compared to similar results obtained using thin shell elements and hexahedral elements for the beam mesh.

Hourglass Control Convergence Studies for Hexahedral Elements Developed by the ASME Special Working Group on Computational Modeling

The ASME Special Working Group on Computational Modeling for Explicit Dynamics was founded in August 2008 for the purpose of creating a quantitative guidance document for the development of finite element models used to analyze energy-limited events using explicit dynamics software. This document will be referenced in the ASME Code Section III, Division 3 and the next revision of NRC Regulatory Guide 7.6 as a means by which the quality of a finite element model may be judged. One portion of the document will be devoted to a series of convergence studies that demonstrates the effect of hourglass control settings on solution convergence for reduced integration elements. These convergence studies will demonstrate the importance of selecting an appropriate hourglass control setting to achieve accurate results for large deformation simulations using reduced integration elements. In this paper, the authors present the results of a convergence study for an impulsively loaded propped cantilever beam constructed of LS-DYNA reduced integration hexahedral elements using different hourglass control settings. A large load is applied to produce large deformations and large plastic strains in the beam.

Mesh Convergence Studies for Hexahedral Elements Developed by the ASME Special Working Group on Computational Modeling

The ASME Special Working Group on Computational Modeling for Explicit Dynamics was founded in August 2008 for the purpose of creating a quantitative guidance document for the development of finite element models used to analyze energy-limited events using explicit dynamics software. This document will be referenced in the ASME Code Section III, Division 3 and the next revision of NRC Regulatory Guide 7.6 as a means by which the quality of a finite element model may be judged. One portion of the document will be devoted to a series of element convergence studies that can aid designers in establishing the mesh refinement requirements necessary to achieve accurate results for a variety of different element types in regions of high plastic strain. These convergence studies will also aid reviewers in evaluating the quality of a finite element model and the apparent accuracy of its results. In this paper, the authors present the results of a convergence study for an impulsively loaded propped cantilever beam constructed of LS-DYNA hexahedral elements using both reduced and selectively reduced integration. Three loading levels are considered; the first maintains strains within the elastic range, the second induces moderate plastic strains, and the third produces large deformations and large plastic strains.

An Update on the Implementation of Experience-Based Seismic Equipment Qualification in the ASME QME-1 Standard

In 1997, the joint ASME-QME/IEEE-NPEC Special Working Group on Standardization of Experience Based Seismic Qualification developed a recommendation for incorporation of experience-based seismic qualification of equipment into the Qualification of Mechanical Equipment (QME) Standard. In response to this recommendation, the QME Main Committee formed a Subgroup on Dynamic Qualification and chartered this Subgroup to incorporate experience-based seismic qualification of equipment into Appendix A of Section QR of the QME-1 Standard. This paper provides an update on the progress of the ASME QME Subgroup on Dynamic Qualification in developing an update to the QME-1 Standard that will include the use of earthquake experience for the seismic qualification of mechanical equipment used in nuclear facilities.

Background to Recent Revision of the Section III Seismic Piping Rules

The new rules for seismic piping design in Section III that were developed and included in the requirements in 1994 Addenda of the ASME Boiler and Pressure Vessel Code (B&PV Code) generated considerable discussion within the industry and from the United States Nuclear Regulatory Commission, (USNRC). The USNRC initiated a review of the results of the previous EPRI/NRC experimental program and the Japanese industry started its own experimental program. To accommodate and address developments resulting from these efforts, the ASME, B&PV Code established a Special Working Group (SWG) to continue the review and study of the questions and information generated. This paper reports on the efforts of this SWG which resulted in refinements of the revised rules. These refinements have been accepted for inclusion in Section III of the ASME, B&PV Code.