Juvenile primary fibromyalgia syndrome: A Review- Treatment and Prognosis

Juvenile primary fibromyalgia syndrome (JPFS) is a chronic musculoskeletal pain syndrome affecting children and adolescents. In part one of this review, we discussed the epidemiology, etiology, pathogenesis, clinical manifestations and diagnosis of JPFS. Part two focuses on the treatment and prognosis of JPFS. Early intervention is important. The standard of care is multidisciplinary, combining various modalities—most importantly, exercise and cognitive behavioral therapy. Prognosis varies and symptoms may persist into adulthood.

Juvenile primary Fibromyalgia Syndrome: epidemiology, etiology, pathogenesis, clinical manifestations and diagnosis

Juvenile primary fibromyalgia syndrome (JPFS) is a chronic, musculoskeletal pain syndrome affecting children and adolescents, most commonly adolescent girls. The syndrome has a multifactorial etiology, with altered central pain processing playing an important role. The hallmark symptom is severe, widespread musculoskeletal pain. Other symptoms include sleep and mood disturbances, headaches, stiffness, and subjective joint swelling. Physical examination can reveal multiple tender points. The diagnosis is clinical, with defined criteria. Early diagnosis and intervention are important. In this part of the review, we discuss the epidemiology, etiology, pathogenesis, clinical manifestations and diagnosis of JPFS. Part two will focus on treatment and prognosis.

Primary fibromyalgia syndrome: A new holistic approach [abstract]

INTRODUCTION: Primary fibromyalgia syndrome (PFS) is a psychogenic form of rheumatism characterized by nonspecific persistent chronic pain for at least six months at the trigger points (8 to 30 Trigger Points), short-term memory loss, difficulty concentrating, morning muscle rigidity, restless leg syndrome, cramps, neuro-vegetative disturbance, weakness, change in sleep pattern, anxiety, reactive depression, functional colopathy disturbance, sexual disturbance, persistent low-grade fever, interstitial cystitis, postural instability with vertigo and tinnitus. They present: a)viral etiology from: Epstein-Barr virus with pyscho-somatic substrate. b)Immune factors: inflammatory cytokine IL-1, T.N.F. alpha. c)Organic etiology: alteration of biochemical and morphological markers, metabolic oxidative stress. d)Psychological or traumatic stress : anxiety, reactive depression, panic attacks whiplash. e)Environmental factors : change in electromagnetic fields, geopathic stress, pesticide poisoning with multiple chemical syndrome, mercury poisoning. f)Dietary factors : presence of glutamate in food. g)Gulf war syndrome : 30% of soldiers develop P. F. S. MATERIAL and METHODS: The patient is evaluated from a psychological point of view (psychological trauma), associated with the use of Acetyl-L-Carnitine, Naltrexone hydrocloride low dose and Cell Food-S-Adenosin Methionine. With additional therapies : Mineralogram , Chelation Therapy , Viral Seriology with Labò Live , Micro-immunotherapy (with homeopathic interleukin), Dr. Pierpaoli protocol with the use of vitamins A, D, E, C, Melatonin, Glutathione, Ubiquinone. Protocol: -Infiltration of the Trigger Points, mix of oxygen-ozone (O2O3) concentration 15-10 mcgrg/mL in cycles assessed with the Kinesiology Test (K.T.) -Minor Autohemotherapy (PAET) : concentration 20-15-10 mcgr/mL in cycles (K.T.) -Major Autohemotherapy (GAET) : concentration 20-15-10 mcgr/mL in cycles (K.T.) -Rectal insufflation (R.I.) : concentration 20-15-10 mcgr/mL in cycles (K.T.) From 1988 to 2017, I have treated 900 cases with this method, with the following results : significant symptom remission in the secondary form in around 60-70% of patients treated with infiltration of the Trigger Points and PAET. In more resistant cases, I have used homotoxicology, psychological counseling, Dr. Pierpaoli protocol and micro-immunotherapy RESULTS: These method results in good symptom remission in 50-60% of the cases treated. CONCLUSIONS: In the multi-factor genesis of PFS, an early diagnosis is important to prevent the pain occurring alongside psycho-somatic disturbances, which lead the subject into a reactive-depressive state. In the complex symptom variety, the obtained percentage results have improved with this additional method, as, by alleviating the symptoms, you assure a better quality of life for the patient.