DO POOR ENVIRONMENTAL CONDITIONS DRIVE TRACHOMA TRANSMISSION IN BURUNDI? A MATHEMATICAL MODELLING STUDY

Trachoma is an infectious disease and it is the leading cause of preventable blindness worldwide. To achieve its elimination, the World Health Organization set a goal of reducing the prevalence in endemic areas to less than $5$ % by 2020, utilizing the SAFE (surgery, antibiotics, facial cleanliness, environmental improvement) strategy. However, in Burundi, trachoma prevalences of greater than $5$ % are still reported in 11 districts and it is hypothesized that this is due to the poor implementation of the environmental improvement factor of the SAFE strategy. In this paper, a model based on an ordinary differential equation, which includes an environmental transmission component, is developed and analysed. The model is calibrated to recent field data and is used to estimate the reductions in trachoma that would have occurred if adequate environmental improvements were implemented in Burundi. Given the assumptions in the model, it is clear that environmental improvement should be considered as a key component of the SAFE strategy and, hence, it is crucial for eliminating trachoma in Burundi.

NUMERICAL SOLUTIONS TO A FRACTIONAL DIFFUSION EQUATION USED IN MODELLING DYE-SENSITIZED SOLAR CELLS

Dye-sensitized solar cells consistently provide a cost-effective avenue for sources of renewable energy, primarily due to their unique utilization of nanoporous semiconductors. Through mathematical modelling, we are able to uncover insights into electron transport to optimize the operating efficiency of the dye-sensitized solar cells. In particular, fractional diffusion equations create a link between electron density and porosity of the nanoporous semiconductors. We numerically solve a fractional diffusion model using a finite-difference method and a finite-element method to discretize space and an implicit finite-difference method to discretize time. Finally, we calculate the accuracy of each method by evaluating the numerical errors under grid refinement.

A MESHLESS LOCAL GALERKIN INTEGRAL EQUATION METHOD FOR SOLVING A TYPE OF DARBOUX PROBLEMS BASED ON RADIAL BASIS FUNCTIONS

The main goal of this paper is to solve a class of Darboux problems by converting them into the two-dimensional nonlinear Volterra integral equation of the second kind. The scheme approximates the solution of these integral equations using the discrete Galerkin method together with local radial basis functions, which use a small set of data instead of all points in the solution domain. We also employ the Gauss–Legendre integration rule on the influence domains of shape functions to compute the local integrals appearing in the method. Since the scheme is constructed on a set of scattered points and does not require any background meshes, it is meshless. The error bound and the convergence rate of the presented method are provided. Some illustrative examples are included to show the validity and efficiency of the new technique. Furthermore, the results obtained demonstrate that this method uses much less computer memory than the method established using global radial basis functions.

BOUNDS ON THE CRITICAL TIMES FOR THE GENERAL FISHER–KPP EQUATION

The Fisher–Kolmogorov–Petrovsky–Piskunov (Fisher–KPP) equation is one of the prototypical reaction–diffusion equations and is encountered in many areas, primarily in population dynamics. An important consideration for the phenomena modelled by diffusion equations is the length of the diffusive process. In this paper, three definitions of the critical time are given, and bounds are obtained by a careful construction of the upper and lower solutions. The comparison functions satisfy the nonlinear, but linearizable, partial differential equations of Fisher–KPP type. Results of the numerical simulations are displayed. Extensions to some classes of reaction–diffusion systems and an application to a spatially heterogeneous harvesting model are also presented.

INTERACTION OF A SINGULAR SURFACE WITH A STRONG SHOCK IN THE INTERSTELLAR GAS CLOUDS

We investigate the interaction between a singular surface and a strong shock in the self-gravitating interstellar gas clouds with the assumption of spherical symmetry. Using the method of the Lie group of transformations, a particular solution of the flow variables and the cooling–heating function for an infinitely strong shock is obtained. This paper explores an application of the singular surface theory in the evolution of an acceleration wave front propagating through an unperturbed medium. We discuss the formation of an acceleration, considering the cases of compression and expansion waves. The influence of the cooling–heating function on a shock formation is explained. The results of a collision between a strong shock and an acceleration wave are discussed using the Lax evolutionary conditions.

ALGORITHM TO CONSTRUCT INTEGRO SPLINES

We study some properties of integro splines. Using these properties, we design an algorithm to construct splines $S_{m+1}(x)$ of neighbouring degrees to the given spline $S_m(x)$ with degree m. A local integro-sextic spline is constructed with the proposed algorithm. The local integro splines work efficiently, that is, they have low computational complexity, and they are effective for use in real time. The construction of nonlocal integro splines usually leads to solving a system of linear equations with band matrices, which yields high computational costs.

ON OPTIMAL THRESHOLDS FOR PAIRS TRADING IN A ONE-DIMENSIONAL DIFFUSION MODEL

We study the static maximization of long-term averaged profit, when optimal preset thresholds are determined to describe a pairs trading strategy in a general one-dimensional ergodic diffusion model of a stochastic spread process. An explicit formula for the expected value of a certain first passage time is given, which is used to derive a simple equation for determining the optimal thresholds. Asymptotic arbitrage in the long run of the threshold strategy is observed.