Dermatitis herpetiformis and bullous pemphigoid. Intermediate and mixed forms

1976 ◽  
Vol 112 (1) ◽  
pp. 45-48 ◽  
Author(s):  
S. Jablonska
Keyword(s):  
Bullous Pemphigoid ◽  
Dermatitis Herpetiformis

Bullous pemphigoid and dermatitis herpetiformis association: A genetic predisposition

2013 ◽  
Vol 40 (11) ◽  
pp. 940-941 ◽  
Author(s):  
Fabrizio Vaira ◽  
Valentina Della Valle ◽  
Daniele Fanoni ◽  
Paolo Pontini ◽  
Simona Muratori
Keyword(s):  
Bullous Pemphigoid ◽  
Genetic Predisposition ◽  
Dermatitis Herpetiformis

scholarly journals Bullous Systemic Lupus Erythematosus

2018 ◽  
Vol 19 (2) ◽  
pp. 123-125
Author(s):  
Sk Jakaria Been Sayeed ◽  
Md Mujibur Rahman ◽  
AKM Humayon Kabir ◽  
Md Moniruzzaman ◽  
Uzzal Mallik ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Bullous Pemphigoid ◽  
Epidermolysis Bullosa ◽  
Lupus Erythematosus ◽  
Dermatitis Herpetiformis ◽  
Epidermolysis Bullosa Acquisita ◽  
Systemic Lupus ◽  
Type Vii Collagen ◽  
Linear Iga Disease ◽  
Distinct Disease

Bullous systemic lupus erythematosus (BSLE) is extremely rare but distinct disease, characterized by vesicobullous skin eruptions in systemic lupus erythematosus (SLE). It can develop either before or after a diagnosis of SLE has been established. BSLE is characterized by a dermatitis herpetiformis-like histology and an autoimmunity to type VII collagen. It must be differentiated from other autoimmune vesicobullous diseases such as epidermolysis bullosa acquisita, dermatitis herpetiformis, linear IgA disease, and bullous pemphigoid. Its important to combine clinical, histological, and immunofluorescence findings to establish a diagnosis of BSLE. We report a case of BSLE to illustrate and emphasize the need for an integrative diagnostic approach.J MEDICINE JUL 2018; 19 (2) : 123-125

Histology of linear IgA disease, dermatitis herpetiformis, and bullous pemphigoid

1983 ◽  
Vol 5 (6) ◽  
pp. 547-554 ◽  
Author(s):  
W. K. Blenkinsopp ◽  
G. P. Haffenden ◽  
L. Fry ◽  
J. N. Leonard
Keyword(s):  
Bullous Pemphigoid ◽  
Dermatitis Herpetiformis ◽  
Linear Iga Disease

Expression of selected ADAMs in bullous pemphigoid and dermatitis herpetiformis

2009 ◽  
Vol 56 (1) ◽  
pp. 58-61 ◽  
Author(s):  
Agnieszka Zebrowska ◽  
Malgorzata Wagrowska-Danilewicz ◽  
Marian Danilewicz ◽  
Karolina Wodz ◽  
Milena Sokolowska ◽  
...  
Keyword(s):  
Bullous Pemphigoid ◽  
Dermatitis Herpetiformis

scholarly journals The Role of Intereukin-31 in Pathogenesis of Itch and Its Intensity in a Course of Bullous Pemphigoid and Dermatitis Herpetiformis

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Lilianna Kulczycka-Siennicka ◽  
Anna Cynkier ◽  
Elżbieta Waszczykowska ◽  
Anna Woźniacka ◽  
Agnieszka Żebrowska
Keyword(s):  
Signaling Pathway ◽  
Bullous Pemphigoid ◽  
Dermatitis Herpetiformis ◽  
Subjective Symptoms ◽  
Autoimmune Blistering Disease ◽  
Stat Signaling ◽  
Blistering Disease ◽  
Autoimmune Blistering Diseases

Itch which is one of the major, subjective symptoms in a course of bullous pemphigoid and dermatitis herpetiformis makes those two diseases totally different than other autoimmune blistering diseases. Its pathogenesis is still not fully known. The aim of this research was to assess the role of IL-31 in development of itch as well as to measure its intensity. Obtained results, as well as literature data, show that lower concentration of IL-31 in patients’ serum may be correlated with its role in JAK/STAT signaling pathway which is involved in development of autoimmune blistering disease. Intensity of itch is surprisingly huge problem for the patients and the obtained results are comparable with results presented by atopic patients.

scholarly journals Expression of the JAK/STAT Signaling Pathway in Bullous Pemphigoid and Dermatitis Herpetiformis

2017 ◽  
Vol 2017 ◽  
pp. 1-12 ◽  
Author(s):  
K. Juczynska ◽  
A. Wozniacka ◽  
E. Waszczykowska ◽  
M. Danilewicz ◽  
M. Wagrowska-Danilewicz ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Bullous Pemphigoid ◽  
Target Genes ◽  
Dermatitis Herpetiformis ◽  
Skin Lesions ◽  
Control Group ◽  
Cytokine Network ◽  
Activation Of Transcription ◽  
Autoimmune Bullous Diseases ◽  
Stat Signaling

A family of eleven proteins comprises the Janus kinases (JAK) and signal transducers and activators of transcription (STAT) signaling pathway, which enables transduction of signal from cytokine receptor to the nucleus and activation of transcription of target genes. Irregular functioning of the cascade may contribute to pathogenesis of autoimmune diseases; however, there are no reports concerning autoimmune bullous diseases yet to be published. The aim of this study was to evaluate the expression of proteins constituting the JAK/STAT signaling pathway in skin lesions and perilesional area in dermatitis herpetiformis (DH) and bullous pemphigoid (BP), as well as in the control group. Skin biopsies were collected from 21 DH patients, from 20 BP patients, and from 10 healthy volunteers. The localization and expression of selected STAT and JAK proteins were examined by immunohistochemistry and immunoblotting. We found significantly higher expression of JAK/STAT proteins in skin lesions in patients with BP and DH, in comparison to perilesional skin and the control group, which may be related to proinflammatory cytokine network and induction of inflammatory infiltrate in tissues. Our findings suggest that differences in the JAK and STAT expression may be related to distinct cytokines activating them and mediating neutrophilic and/or eosinophilic infiltrate.

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