Potassium iodide in the treatment of erythema nodosum and nodular vasculitis

1981 ◽  
Vol 117 (1) ◽  
pp. 29-31 ◽  
Author(s):  
T. Horio
Keyword(s):  
Potassium Iodide ◽  
Erythema Nodosum ◽  
Nodular Vasculitis

scholarly journals Potassium Iodide for Cutaneous Inflammatory Disorders: A Monocentric, Retrospective Study

Dermatology ◽  
2018 ◽  
Vol 235 (2) ◽  
pp. 137-143 ◽  
Author(s):  
Florian Anzengruber ◽  
Caroline Mergenthaler ◽  
Carla Murer ◽  
Reinhard Dummer
Keyword(s):  
Potassium Iodide ◽  
Erythema Nodosum ◽  
Therapy Response ◽  
University Hospital ◽  
Cutaneous Sarcoidosis ◽  
Study Results ◽  
Perioral Dermatitis ◽  
Progression Of Disease ◽  
Skin Conditions ◽  
Nodular Vasculitis

Objectives: Potassium iodide (KI) is a medication that has been used for decades in dermatology and it is mentioned as a treatment option in all major dermatology textbooks. Yet, there is little recent information on its efficacy. In our study, we wanted to retrospectively evaluate the therapy response to KI in our patients. Methods: The hospital information system was searched for patients treated with KI at the Department of Dermatology (University Hospital Zurich) in the last 20 years (January 1, 1998 to December 31, 2017). A total of 52 patients were found and, subsequently, 35 patients were included in our study. Results: KI was prescribed for the following skin conditions: erythema nodosum, disseminated granuloma anulare, necrobiosis lipoidica, nodular vasculitis, cutaneous sarcoidosis, and granulomatous perioral dermatitis/ rosacea. The median duration of KI intake was 5 ± 7.7 weeks (range 1–26). The global assessment of efficacy by the treating physician showed an improvement of disease in about a third of all patients. No response was seen in 14 patients and 9 even had a progression of disease. An adverse event was documented in 16 cases. Conclusions: Our findings show that an improvement was reached in only about a third of all cases. High response rates with only mild side effects (in 16 out of 35 patients) were observed.

ERYTHEMA NODOSUM VERSUS NODULAR VASCULITIS

1993 ◽  
Vol 32 (2) ◽  
pp. 108-112 ◽  
Author(s):  
MARIA-DOLORES SANZ VICO ◽  
VICTOR DIEGO ◽  
EVARISTO SÁNCHEZ YUS
Keyword(s):  
Erythema Nodosum ◽  
Nodular Vasculitis

scholarly journals Erythema induratum of Bazin associated with Addison's disease: first description

2012 ◽  
Vol 130 (6) ◽  
pp. 405-408 ◽  
Author(s):  
Rodrigo Antonio Brandão Neto ◽  
Jozélio Freire de Carvalho
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Polyarteritis Nodosa ◽  
Erythema Nodosum ◽  
Addison’S Disease ◽  
Tuberculin Test ◽  
Signs And Symptoms ◽  
Addison's Disease ◽  
Bacillus Calmette Guerin ◽  
Nodular Vasculitis

CONTEXT: Erythema induratum of Bazin (EIB) is considered to be a tuberculid reaction and consists of recurrent painful nodules. The differential diagnosis includes diseases like nodular vasculitis, perniosis, polyarteritis nodosa and erythema nodosum. CASE REPORT: We report the case of a woman with EIB who developed Addison's disease during treatment with anti-tuberculosis drugs with good response to glucocorticoid replacement. The diagnosis was obtained through the clinical picture, positive tuberculin test and positive BCG (bacillus Calmette-Guérin) test on the histological sample. Anti-tuberculosis drugs and glucocorticoid replacement led to disappearance of the signs and symptoms. CONCLUSIONS: This is the first description of an association between EIB and Addison's disease. It should be borne in mind that tuberculosis is an important etiological factor for Addison's disease.

scholarly journals Mycobacterium tuberculosis Infection Is Associated with the Development of Erythema Nodosum and Nodular Vasculitis

PLoS ONE ◽  
2013 ◽  
Vol 8 (5) ◽  
pp. e62653 ◽  
Author(s):  
Sheng’an Chen ◽  
Jiazhen Chen ◽  
Lianjun Chen ◽  
Qiao’an Zhang ◽  
Xiaoqun Luo ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Erythema Nodosum ◽  
Tuberculosis Infection ◽  
Mycobacterium Tuberculosis Infection ◽  
Nodular Vasculitis

NSAIDs in Dermatologic Therapy: Review and Preview

2002 ◽  
Vol 6 (5) ◽  
pp. 449-459 ◽  
Author(s):  
Edward S. Friedman ◽  
Nicole LaNatra ◽  
Matthew J. Stiller
Keyword(s):  
Erythema Nodosum ◽  
Systemic Mastocytosis ◽  
Treatment And Prevention ◽  
Non Melanoma Skin Cancer ◽  
Inflammatory Drugs ◽  
Nodular Vasculitis ◽  
Innovative Drugs ◽  
Cox 2 Inhibitors ◽  
Melanoma Skin

Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) have been an important therapy in the treatment of a large number of cutaneous pathologies for more than three decades. Objective: In this retrospective review, we document the use of NSAIDs in more than 15 common and uncommon dermatoses, including acne, psoriasis, sunburn, erythema nodosum, cryoglobulinemia, Sweet's syndrome, systemic mastocytosis, as well as urticarial, livedoid, and nodular vasculitis. NSAIDs act mainly by inhibiting prostaglandin synthesis by the cyclooxygenase (COX) pathway. Conclusion: Recent studies link prostaglandin to cutaneous carcinogenesis, thus expanding the dermatologic use of NSAIDs. They may be effective in the treatment and prevention of non-melanoma skin cancer, and specific COX-2 inhibitors promise safer, broader, long-term use of these pharmacologically innovative drugs.

scholarly journals Successful Therapy of Refractory Erythema Nodosum Associated with Crohn's Disease Using Potassium Iodide

1997 ◽  
Vol 11 (6) ◽  
pp. 501-502 ◽  
Author(s):  
John K Marshall ◽  
E Jan Irvine
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Potassium Iodide ◽  
Mechanism Of Action ◽  
Systemic Corticosteroid ◽  
Erythema Nodosum ◽  
Controlled Trial ◽  
Skin Involvement ◽  
Successful Therapy ◽  
Extraintestinal Manifestation

Erythema nodosum is a common extraintestinal manifestation of Crohn's disease. While mild skin involvement often responds to conservative management, severe or refractory cases may require systemic corticosteroid or immunosuppressive therapy. This report describes successful treatment of severe, refractory erythema nodosum associated with Crohn's colitis using oral potassium iodide. While the mechanism of action of this agent is poorly understood, it appears to be an effective and nontoxic therapy for Crohn's-related erythema nodosum and warrants further evaluation in a placebo controlled trial.

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