Operating Table for Guinea Pig Ear Surgery

1978 ◽  
Vol 104 (3) ◽  
pp. 177-178 ◽  
Author(s):  
R. T. Watson ◽  
W. G. Leslie ◽  
E. H. Jennings
Keyword(s):  
Guinea Pig ◽  
Operating Table ◽  
Ear Surgery

Safety and efficacy of carbomethylcellulose foam in guinea pig middle ear surgery

2010 ◽  
Vol 142 (3) ◽  
pp. 405-408 ◽  
Author(s):  
Patrick J. Antonelli ◽  
Edith M. Sampson ◽  
Dustin M. Lang
Keyword(s):  
Guinea Pig ◽  
Middle Ear ◽  
Middle Ear Surgery ◽  
Ear Surgery ◽  
Safety And Efficacy

Effects of lonomer Cement on Guinea Pig Cochleas

1997 ◽  
Vol 76 (4) ◽  
pp. 223-230 ◽  
Author(s):  
Taisuke Kobayashi ◽  
Yasuyuki Hinohira ◽  
Masamitsu Hyodo ◽  
Goran Bredberg ◽  
Edel Alsterborg
Keyword(s):  
Hearing Loss ◽  
Guinea Pig ◽  
Guinea Pigs ◽  
Morphological Study ◽  
Round Window ◽  
Cell Loss ◽  
Round Window Membrane ◽  
Hair Cell Loss ◽  
Ear Surgery ◽  
Hearing Thresholds

The inner ear toxicity of ionomeric cement (lonocem®) when used as a reconstructive material in ear surgery was evaluated in 47 guinea pigs used in a morphological study. The cement was implanted on either the promontory, the round window membrane or the stapes. There was no significant hair cell loss compared with the control ear at three weeks, two months or three months after implantation. Using electrocochleography, the hearing thresholds before, and three weeks, two and three months after the implantation were compared in an additional seven animals. No evident hearing loss was observed in any animal during the study period. No morphological or functional evidence for an ototoxic effect of the ionomeric cement was found in this study.

A Novel 3D-Printed Head Holder for Guinea Pig Ear Surgery

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Chris Valentini ◽  
Young Jae Ryu ◽  
Betsy Szeto ◽  
Michelle Yu ◽  
Anil K. Lalwani ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Ear Surgery ◽  
Head Holder ◽  
3D Printed

Defining the Hook Region Anatomy of the Guinea Pig Cochlea for Modeling of Inner Ear Surgery

2017 ◽  
Vol 38 (6) ◽  
pp. e179-e187 ◽  
Author(s):  
Jonathon Lo ◽  
Phillip Sale ◽  
Sudanthi Wijewickrema ◽  
Luke Campbell ◽  
Hayden Eastwood ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Inner Ear ◽  
Ear Surgery ◽  
Guinea Pig Cochlea ◽  
Inner Ear Surgery

Second Place — Resident Clinical Science Award 1993: Effect of Otologic Drill Noise on ABR Thresholds in a Guinea Pig Model

1993 ◽  
Vol 109 (4) ◽  
pp. 660-667 ◽  
Author(s):  
Gregg W. Suits ◽  
Robert E. Brummett ◽  
Jim Nunley
Keyword(s):  
Guinea Pig ◽  
Auditory Brainstem Response ◽  
Auditory Brainstem ◽  
Pig Model ◽  
Threshold Shift ◽  
Ear Surgery ◽  
Sound Exposure ◽  
Brainstem Response ◽  
Guinea Pig Model ◽  
Mastoid Surgery

The Noise Generated By The Otologic Drill Has Been Implicated As A Cause Of Sensorineural Hearing Loss After Ear Surgery. However, Clinical Studies On This Subject Are Contradictory And Difficult To Interpret. Therefore A Guinea Pig Model Was Used To Study Whether The Level Of Noise Generated By The Otologic Drill Can Cause Threshold Shifts In The Auditory Brainstem Response (Abr). The Source Noise Was A Recording Obtained During A Human Cadaver Mastoidectomy Using A Microphone And An Accelerometer. Ten Female Topeka-Strain Guinea Pigs Were Exposed To The Recorded Drill Noise For A Period Of 55 Minutes. Exposure Included Both Air-Conducted Energy From A Speaker And Bone-Conducted Energy From A Bone Vibrator Applied Directly To The Skull. Abr Threshold Measurements Were Taken Pre-Exposure (Baseline), Immediately After Exposure, And At Weekly Intervals Thereafter For 3 Weeks. Three Control Animals Were Subjected To The Same Procedure Without The Sound Exposure. A Significant Threshold Shift ( P > 0.0001) Was Seen For Each Frequency Tested (2, 4, 8, 16, 20, And 32 Khz) Immediately After Exposure To Noise In All Experimental Animals. Thresholds Returned To Baseline Within 3 Weeks. We Conclude That The Level Of Noise Generated By The Otologic Drill In Mastoid Surgery Can Cause A Temporary Threshold Shift In This Guinea Pig Model

Effect of Contraceptive Steroids on the Endometrium of Guinea Pig: SEM study

1977 ◽  
Vol 35 ◽  
pp. 668-669
Author(s):  
Mai M. Said ◽  
Ramesh K. Nayak ◽  
Randall E. McCoy
Keyword(s):  
Guinea Pig ◽  
Reproductive Tract ◽  
Three Dimensional ◽  
Female Reproductive Tract ◽  
Human Female ◽  
Surface Ultrastructure ◽  
Transmission Electron ◽  
Sem Study ◽  
Uterine Mucosa ◽  
Group 1

Burgos and Wislocki described changes in the mucosa of the guinea pig uterus, cervix and vagina during the estrous cycle investigated by transmission electron microscopy. More recently, Moghissi and Reame reported the effects of progestational agents on the human female reproductive tract. They found drooping and shortening of cilia in norgestrel and norethindrone- treated endometria. To the best of our knowledge, no studies concerning the effects of mestranol and norethindrone given concurrently on the three-dimensional surface features on the uterine mucosa of the guinea pig have been reported. The purpose of this study was to determine the effect of mestranol and norethindrone on surface ultrastructure of guinea pig uterus by SEM.Seventy eight animals were used in this study. They were allocated into two groups. Group 1 (20 animals) was injected intramuscularly 0.1 ml vegetable oil and served as controls.

Ultrastructure and Drug Metabolism in the Developing Guinea Pig

1973 ◽  
Vol 31 ◽  
pp. 538-539
Author(s):  
W. Kuenzig ◽  
M. Boublik ◽  
J.J. Kamm ◽  
J.J. Burns
Keyword(s):  
Guinea Pig ◽  
Metabolic Activity ◽  
Animal Species ◽  
Adult Animal ◽  
Smooth Endoplasmic Reticulum ◽  
Fetal Life ◽  
Mixed Function Oxidase ◽  
Cytochrome P 450 ◽  
Microsomal Mixed Function Oxidase ◽  
Mixed Function Oxidase Activity

Unlike a variety of other animal species, such as the rabbit, mouse or rat, the guinea pig has a relatively long gestation period and is a more fully developed animal at birth. Kuenzig et al. reported that drug metabolic activity which increases very slowly during fetal life, increases rapidly after birth. Hepatocytes of a 3-day old neonate metabolize drugs and reduce cytochrome P-450 at a rate comparable to that observed in the adult animal. Moreover the administration of drugs like phenobarbital to pregnant guinea pigs increases the microsomal mixed function oxidase activity already in the fetus.Drug metabolic activity is, generally, localized within the smooth endoplasmic reticulum (SER) of the hepatocyte.

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