TYPE SPECIFIC POLYSACCHARIDE SKIN TEST IN SERUM THERAPY OF PNEUMONIA

1939 ◽  
Vol 113 (21) ◽  
Author(s):  
JOSEPH C. EDWARDS ◽  
CHARLES L. HOAGLAND ◽  
LAWRENCE D. THOMPSON
Keyword(s):  
Skin Test ◽  
Specific Polysaccharide ◽  
Serum Therapy

scholarly journals THE VALUE OF THE SKIN TEST WITH TYPE-SPECIFIC CAPSULAR POLYSACCHARIDE IN THE SERUM TREATMENT OF TYPE I PNEUMOCOCCUS PNEUMONIA

1933 ◽  
Vol 57 (4) ◽  
pp. 617-631 ◽  
Author(s):  
Thomas Francis
Keyword(s):  
Skin Reaction ◽  
Skin Test ◽  
Capsular Polysaccharide ◽  
Skin Tests ◽  
Type I ◽  
Agglutination Reaction ◽  
Positive Skin ◽  
Specific Antibodies ◽  
Circulating Antibodies ◽  
Serum Therapy

Skin tests were made with Type I S.S.S. in 53 cases of Type I pneumococcus lobar pneumonia, 48 of which were treated with antipneumococcus Type I serum. In all but 1 of the 46 recovered cases a positive, immediate skin reaction was obtained at about the time of recovery. In 7 fatal cases reactions were consistently negative, even in the presence of circulating type-specific antibodies. The skin test has proved to be an extremely valuable guide to serum therapy, and a definite prognostic aid. The test has distinct advantages over the agglutination reaction in that it is not merely an index of circulating antibodies. When positive, it invariably denotes that recovery has begun; when negative, it indicates further serum therapy. The mechanism of the positive skin test is closely related to that operative in recovery from pneumonia, and is apparently the resultant of antibody and tissue activity.

Sequential degranulation of eosinophils induced by antigen or autocoids in allergic humans

1986 ◽  
Vol 44 ◽  
pp. 354-355
Author(s):  
Kate W. Sjoerdsma ◽  
W. James Metzger
Keyword(s):  
Allergic Rhinitis ◽  
Bronchoalveolar Lavage ◽  
Allergic Asthma ◽  
Skin Test ◽  
Positive Skin Test ◽  
Positive Skin ◽  
Human Eosinophil ◽  
Asthmatic Patients ◽  
Allergic Asthmatic ◽  
History Of

Eosinophils are important to the pathogenesis of allergic asthma, and are increased in bronchoalveolar lavage within four hours after bronchoprovocation of allergic asthmatic patients, and remain significantly increased up to 24 hours later. While the components of human eosinophil granules have been recently isolated and purified, the mechanisms of degranulation have yet to be elucidated.We obtained blood from two volunteers who had a history of allergic rhinitis and asthma and a positive skin test (5x5mm wheal) to Alternaria and Ragweed. Eosinophils were obtained using a modification of the method described by Roberts and Gallin.

Skin test and crossreactivity studies with Euroglyphus maynei and Dermatophagoides pteronyssinus

1997 ◽  
Vol 27 (8) ◽  
pp. 893-897 ◽  
Author(s):  
S. F. KEMP ◽  
R. F. LOCKEY ◽  
E. FERNANDEZ-CALDAS ◽  
L. G. ARLIAN
Keyword(s):  
Skin Test ◽  
Dermatophagoides Pteronyssinus ◽  
Euroglyphus Maynei

General considerations for skin test procedures in the diagnosis of drug hypersensitivity

Allergy ◽  
2002 ◽  
Vol 57 (1) ◽  
pp. 45-51 ◽  
Author(s):  
K. Brockow ◽  
A. Romano ◽  
M. Blanca ◽  
J. Ring ◽  
W. Pichler ◽  
...  
Keyword(s):  
Skin Test ◽  
Drug Hypersensitivity ◽  
Test Procedures
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