Sepsis, which is a highly heterogeneous syndrome, can result in death as a consequence of a
systemic inflammatory response syndrome. The activation and regulation of the immune system play a
key role in the initiation, development and prognosis of sepsis. Due to the different periods of sepsis
when the objects investigated were incorporated, clinical trials often exhibit negative or even contrary
results. Thus, in this review we aim to sort out the current knowledge in how immune cells play a role
during sepsis.