The Cochrane Collaboration. Preparing, maintaining, and disseminating systematic reviews of the effects of health care

JAMA ◽  
1995 ◽  
Vol 274 (24) ◽  
pp. 1935-1938 ◽  
Author(s):  
L. Bero
2003 ◽  
Vol 8 (1) ◽  
pp. 11-15 ◽  
Author(s):  
Helen HG Handoll ◽  
Rajan Madhok ◽  
Tracey E Howe

This paper describes the work of the Cochrane Collaboration in producing systematic reviews of health care interventions. It examines the present and potential relevance of Cochrane reviews to clinicians providing hand therapy and gives some pointers for those who wish to take a more active role in evaluating the evidence for their clinical practice.


1997 ◽  
Vol 27 (3) ◽  
pp. 283-292 ◽  
Author(s):  
Sube Banerjee ◽  
Edward Dickinson

Objective: The purpose of this article is to present the current status and future needs of old age psychiatry in relation to evidence-based health care. Method: The opportunities and difficulties of evidence-based medicine as applied to old age psychiatry are described. Depression is used as a specific example. The role of the Cochrane Collaboration and of clinical guidelines in dealing with these difficulties are discussed. Results: There has been a tendency for drug studies to focus on younger age groups and to exclude patients with comorbidity or polypharmacy. Aspects of clinical management separate from drugs are given insufficient attention. The generalizability of current studies is a problem in old age psychiatry. Conclusions: Psychiatry is no less part of medicine than any other specialty. Increased attention to studies of effectiveness, as opposed to efficacy, is indicated. The Cochrane Collaboration is an international network which promotes and conducts systematic reviews of the effectiveness of health care. Systematic reviews can increase the generalizability of the current knowledge base and better define the needs for future research.


2021 ◽  
Vol 7 (1) ◽  
pp. e000920
Author(s):  
Dimitris Challoumas ◽  
Neal L Millar

ObjectiveTo critically appraise the quality of published systematic reviews (SRs) of randomised controlled trials (RCTs) in tendinopathy with regard to handling and reporting of results with special emphasis on strength of evidence assessment.Data sourcesMedline from inception to June 2020.Study eligibilityAll SRs of RCTs assessing the effectiveness of any intervention(s) on any location of tendinopathy.Data extraction and synthesisIncluded SRs were appraised with the use of a 12-item tool devised by the authors arising from the Preferred Reporting Items in Systematic Reviews and Meta-Analyses statement and other relevant guidance. Subgroup analyses were performed based on impact factor (IF) of publishing journals and date of publication.ResultsA total of 57 SRs were included published in 38 journals between 2006 and 2020. The most commonly used risk-of-bias (RoB) assessment tool and strength of evidence assessment tool were the Cochrane Collaboration RoB tool and the Cochrane Collaboration Back Review Group tool, respectively. The mean score on the appraisal tool was 46.5% (range 0%–100%). SRs published in higher IF journals (>4.7) were associated with a higher mean score than those in lower IF journals (mean difference 26.4%±8.8%, p=0.004). The mean score of the 10 most recently published SRs was similar to that of the first 10 published SRs (mean difference 8.3%±13.7%, p=0.54). Only 23 SRs (40%) used the results of their RoB assessment in data synthesis and more than half (n=30; 50%) did not assess the strength of evidence of their results. Only 12 SRs (21%) assessed their strength of evidence appropriately.ConclusionsIn light of the poor presentation of evidence identified by our review, we provide recommendations to increase transparency and reproducibility in future SRs.


1998 ◽  
Vol 65 (3) ◽  
pp. 144-151 ◽  
Author(s):  
Robyn L. Hayes ◽  
John J. McGrath

This paper describes how occupational therapists can become involved in the Cochrane Collaboration — a well-developed tool for facilitating the involvement of health professionals and lay people in evidence-based practice. The Cochrane Collaboration is a growing international project intended to systematically locate, conduct systematic reviews (including metaanalyses) of, and disseminate information on all available randomised controlled trials of interventions in any area of health. In particular, occupational therapists can use the Cochrane Collaboration to become better informed about best practice and evaluate research in their areas of interest, and learn skills related to conducting randomised controlled trials, systematic reviews, and meta-analyses.


2013 ◽  
Vol 23 (2) ◽  
Author(s):  
Claire Glenton ◽  
Sarah Rosenbaum

<p>Cochrane-systematiske oversikter oppleves ofte som lite tilgjengelige. En av hovedaktivitetene til det norske Cochrane-miljøet er å utvikle måter å presentere resultatene fra Cochrane-oversikter på for at de lettere tas i bruk. Vi beskriver her fire hovedprinsipper for dette arbeidet, og gir eksempler på dokumentformater vi har vært med på å utvikle. De overordnete prinsippene er: 1) Informasjonen bør være forståelig for personer uten ekspertkunnskap om forskningsmetodikk. Vi har erfart at når det gjelder forståelsen av resultater fra systematiske oversikter går det største skillet mellom forskere og ikke-forskere og i mindre grad mellom ulike grupper som helsepersonell, pasienter og byråkrater. 2) Informasjonen bør presenteres på en mest mulig nøytral måte. 3) Informasjonen bør være brukertilpasset. Det innebærer at vi innhenter tilbakemeldinger fra sluttbrukere i utviklingsarbeidet og gjør nødvendige tilpasninger i flere omganger. 4) Informasjonsstrukturen bør følge ”1:3:25-prinsippet”. Her presenteres informasjonen både summarisk (1 side), kort oppsummert (3 sider), og mer utdypende (25 sider). I artikkelen beskriver vi flere presentasjonsformater vi har utviklet, blant annet ”Summary of Findings” der resultatene av Cochrane-oversikter presenteres i lettfattelige tabeller; ”plain language summaries”, som er tekstbaserte oppsummeringer rettet mot en bred lesergruppe; ”SUPPORT summaries” rettet mot byråkrater og ”policymakers”; og ”DECIDE Frameworks” der resultatene presenteres sammen med annen informasjon som er relevant i en beslutningsprosess.</p><p>Glenton C, Rosenbaum S. <strong>Cochrane in Norway – How do we disseminate findings from Cochrane reviews?</strong> <em>Nor J Epidemiol</em> 2013; <strong>23</strong> (2): 215-219.</p><p><strong>ENGLISH SUMMARY</strong></p><p>Cochrane systematic reviews are often perceived as inaccessible. One of the main activities of the Norwegian branch of the Cochrane Collaboration is to develop ways to present the results of Cochrane reviews so that they are easier to use. In this paper we describe four main principles that underlie this work, and several of the document formats we have helped produce. Our overarching principles: 1) Information should be understandable for people who do not have expert knowledge about research methodology. When it comes to understanding the results of systematic reviews, we have experienced that the biggest difference is between researchers and non-researchers and to a lesser extent between health personnel, patients and policy makers. 2) Information should be presented in a neutral form. 3) Information should be developed using a user-oriented approach. This involves us collecting responses from the end users in our developmental work and making the necessary adjustments in several phases. 4) The information structure should follow the “1:3:25 principle” where the information is structured in several layers, with increasing level of detail. In this paper, we describe several of the document formats that we have helped develop, including Summary of Findings tables, where we present the results of Cochrane reviews in tables; a plain language summary format where the results are presented as text-based summaries written for a broad user group; SUPPORT summaries written for policy makers; and DECIDE Frameworks, where the results are presented together with other information that may be relevant in a decision making process.</p>


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