Target-controlled infusion versus manually-controlled infusion of propofol for general anaesthesia or sedation in adults

2008 ◽  
Author(s):  
Kate Leslie ◽  
Ornella Clavisi ◽  
Joshua Hargrove
Keyword(s):  
General Anaesthesia ◽  
Target Controlled Infusion

Induction of general anaesthesia by effect-site target-controlled infusion of propofol: influence of pharmacokinetic model and ke0value

Anaesthesia ◽  
2014 ◽  
Vol 69 (5) ◽  
pp. 429-435 ◽  
Author(s):  
A. J. Thomson ◽  
G. Morrison ◽  
E. Thomson ◽  
C. Beattie ◽  
A. F. Nimmo ◽  
...  
Keyword(s):  
General Anaesthesia ◽  
Pharmacokinetic Model ◽  
Effect Site ◽  
Target Controlled Infusion

scholarly journals Correlation of Surgical Pleth Index with Stress Hormones during Propofol-Remifentanil Anaesthesia

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Xinzhong Chen ◽  
Carsten Thee ◽  
Matthias Gruenewald ◽  
Christoph Ilies ◽  
Jan Höcker ◽  
...  
Keyword(s):  
General Anaesthesia ◽  
Sensitivity And Specificity ◽  
Stress Hormones ◽  
High Sensitivity ◽  
Moderate Correlation ◽  
Target Controlled Infusion ◽  
The Relationship

Eighty patients undergoing elective ear-nose-throat surgery were enrolled in the present study to investigate the relationship between surgical pleth index (SPI) and stress hormones (ACTH, cortisol, epinephrine, norepinephrine) during general anaesthesia which was induced and maintained with propofol and remifentanil using a target-controlled infusion. The study concluded that the SPI had moderate correlation to the stress hormones during general anaesthesia, but no correlation during consciousness. Furthermore, SPI values were able to predict ACTH values with high sensitivity and specificity.

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