Antimicrobial-impregnated central venous catheters for prevention of catheter-related bloodstream infection in newborn infants

2014 ◽  
Author(s):  
Munisha Balain ◽  
Sam Oddie ◽  
William McGuire
2009 ◽  
Vol 30 (7) ◽  
pp. 698-701 ◽  
Author(s):  
Stefania Bezzio ◽  
C. Scolfaro ◽  
R. Broglia ◽  
R. Calabrese ◽  
F. Mignone ◽  
...  

This prospective observational study was designed to assess the incidence of, risk factors for, and outcome of catheter-related bloodstream infection in children undergoing cardiac surgery. A staff specifically trained to handle the central venous catheters with proper aseptic techniques and an appropriate patient to medical staff ratio remain the most effective measures to prevent this infection.


2003 ◽  
Vol 31 (1) ◽  
pp. 52-59 ◽  
Author(s):  
Marco Ranucci ◽  
Giuseppe Isgrò ◽  
Pier Paolo Giomarelli ◽  
Marco Pavesi ◽  
Aldo Luzzani ◽  
...  

2019 ◽  
Vol 7 (1) ◽  
Author(s):  
Michael Koeppen ◽  
Franziska Weinert ◽  
Sabrina Oehlschlaeger ◽  
Andreas Koerner ◽  
Peter Rosenberger ◽  
...  

Abstract Background In the critically ill, catheter-related bloodstream infection can result from bacterial contamination of infusion hubs of intravascular catheters. Needle-free connectors (NFC) have been suggested to reduce the rate of bacterial contamination and subsequent catheter-related bloodstream infection (CRBSI), but data remains ambiguous. Thus, we tested if a novel NFC would reduce bacterial contamination and subsequent CRBSI. Results In a prospective, randomized controlled trial, surgical ICU patients were randomized to three-way hubs closed by caps or Bionecteur® (Vygon, Inc.) of central venous catheters. Every 72 h, infusion lines were renewed and microbiological samples were taken. Bacterial growth was analyzed by blinded microbiologists. Incidence of bacterial contamination and CRSBI were assessed. Outcome parameters like length of stay on ICU and outcome were retrospectively assessed. Two thousand seven hundred patients were screened, 111 were randomized to the NFC, and 109 into the control group. Finally, 24 patients in the NFC and 23 control patients were analyzed. The majority of samples (NFC 77%; control 70%) found no bacterial growth. Coagulase-negative staphylococci were most commonly detected on CVC samples (NFC 17%; control 21%). We found CRBSI (defined as identical pathogens in blood culture and catheter line tip culture, and clinical manifestations of infection) in two control patients and one patient of the NFC group. Their length of ICU stay did not differ between groups (NFC 19 days; control 23 days). Conclusion The use of NFC does not influence the rate of bacterial contamination of infusion hubs of central venous catheters. Trial registration Clinicaltrials.gov, NCT02134769. Registered 09 May 2014.


2010 ◽  
Vol 2 (1) ◽  
pp. 5
Author(s):  
Kristen A. Wendorf ◽  
Claudia M. Espinosa ◽  
William D. LeBar ◽  
Jason B. Weinberg

Catheter-related bloodstream infections (CR-BSI) are important complications in patients with long-term indwelling central venous catheters. In this report, we present the case of a 14-year-old male with pulmonary hypertension treated with continuous treprostinil infusion, who presented with a CR-BSI caused by a Tsukamurella species. This case highlights the potential for this unusual organism to cause infection in immunocompetent patients.


2020 ◽  
Vol 41 (7) ◽  
pp. 854-856
Author(s):  
Janita Ferreira ◽  
Paulo Augusto Moreira Camargos ◽  
Viviane Rosado ◽  
Leni Márcia Anchieta ◽  
Roberta Maia de Castro Romanelli

AbstractCatheter-drawn blood sampling is an efficient method of diagnosing catheter-related bloodstream infection (CRBSI) in neonates; it has greater sensitivity and accuracy than methods using catheter-tip cultures. No association was detected between catheter-drawn blood sampling and the occurrence of adverse events with central venous catheters.


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