Bioactive Glass as Synthetic Bone Grafts and Scaffolds for Tissue Engineering

Bio-Glasses ◽  
2012 ◽  
pp. 177-201
Author(s):  
Julian R. Jones
2021 ◽  
Vol 22 (3) ◽  
pp. 1128
Author(s):  
Giulia Battafarano ◽  
Michela Rossi ◽  
Viviana De Martino ◽  
Francesco Marampon ◽  
Luca Borro ◽  
...  

Bone is a regenerative organ characterized by self-renewal ability. Indeed, it is a very dynamic tissue subjected to continuous remodeling in order to preserve its structure and function. However, in clinical practice, impaired bone healing can be observed in patients and medical intervention is needed to regenerate the tissue via the use of natural bone grafts or synthetic bone grafts. The main elements required for tissue engineering include cells, growth factors and a scaffold material to support them. Three different materials (metals, ceramics, and polymers) can be used to create a scaffold suitable for bone regeneration. Several cell types have been investigated in combination with biomaterials. In this review, we describe the options available for bone regeneration, focusing on tissue engineering strategies based on the use of different biomaterials combined with cells and growth factors.


Injury ◽  
2017 ◽  
Vol 48 (12) ◽  
pp. 2807-2813 ◽  
Author(s):  
Alexander Hanke ◽  
Martin Bäumlein ◽  
Siegmund Lang ◽  
Boyko Gueorguiev ◽  
Michael Nerlich ◽  
...  

1998 ◽  
Vol 550 ◽  
Author(s):  
S. Langstaff ◽  
M. Sayer ◽  
T. Smith ◽  
S. Pugh

AbstractSynthetic bone grafts resistant to random dissolution at physiological pH, yet capable of being gradually resorbed in vitro by osteoclasts have been created. Bulk ceramics and ceramic coatings formed from an additive stabilized colloidal sol possess two characteristic features: a phase mixture of calcium hydroxyapatite (HA) and a silicon stabilized tricalcium phosphate, and a microporous morphology based on inter-connected particles (0.2-1.0 μm). The characteristic phase composition arises during sintering through substitution reactions where silicon enters the calcium phosphate lattice under conditions of high chemical reactivity. Evidence for in vitro resorption lacunae on bulk ceramics is presented.


2014 ◽  
Vol 12 (1) ◽  
pp. 354 ◽  
Author(s):  
Yoshinori Imura ◽  
Atsuo Shigi ◽  
Hidetatsu Outani ◽  
Kenichiro Hamada ◽  
Hiromi Tamura ◽  
...  

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