ICH Quality Guidelines

2014 ◽  
pp. 367-380
Author(s):  
Sultan Ghani
Keyword(s):  
2018 ◽  
Vol 3 (1) ◽  
pp. 7-14
Author(s):  
J. Kenneth, R. S. Suglo

Sewage generated in Ghana is commonly discharged into the environment without any form of treatment to reduce the degree ofcontamination and mitigate potential public health and environmental issues. Although some attempts have been made in someparts of Ghana to utilize the waste stabilization pond (WSP) system to treat domestic sewage, the ponds often fail to achievetheir purpose due to lack of basic maintenance and supervision. To assess the utility of the WSP system for treating sewage,wastewater samples were collected from the raw sewage, anaerobic, facultative and maturation ponds of WSPs at Obuasi inGhana, and analyzed for physicochemical and microbiological contaminants. The results show that the final pond effluent meetsrecommended microbiological and chemical quality guidelines. The waste stabilization pond system demonstrates high removalefficiencies of wastewater contaminants. The biochemical oxygen demand, total suspended solids, nitrate and faecal coliformsreduction efficiencies of 97.3%, 97.6%, 83.3% and 99.94% respectively are highly significant, and compare well with reportedremoval efficiencies in the literature. Additionally, the ponds have high reduction efficiencies for heavy metals and pathogenicmicroorganisms. The wastewater treatment system complies with standard wastewater management practices, and provides auseful method for treating and disposing wastewater in Ghana.


1991 ◽  
Vol 23 (1-3) ◽  
pp. 201-209 ◽  
Author(s):  
W. Kreisel

Water quality can affect human health in various ways: through breeding of vectors, presence of pathogenic protozoa, helminths, bacteria and viruses, or through inorganic and organic chemicals. While traditional concern has been with pathogens and gastro-intestinal diseases, chemical pollutants in drinking-water supplies have in many instances reached proportions which affect human health, especially in cases of chronic exposure. Treatment of drinking-water, often grossly inadequate in developing countries, is the last barrier of health protection, but control at source is more effective for pollution control. Several WHO programmes of the International Drinking-Water Supply and Sanitation Decade have stimulated awareness of the importance of water quality in public water supplies. Three main streams have been followed during the eighties: guidelines for drinking-water quality, guidelines for wastewater reuse and the monitoring of freshwater quality. Following massive investments in the community water supply sector to provide people with adequate quantities of drinking-water, it becomes more and more important to also guarantee minimum quality standards. This has been recognized by many water and health authorities in developing countries and, as a result, WHO cooperates with many of them in establishing water quality laboratories and pollution control programmes.


1995 ◽  
Vol 32 (2) ◽  
pp. 281-288
Author(s):  
Susan Taljaard ◽  
Willem A. M. Botes

In South Africa the ultimate goal in water quality management is to keep the water resources suitable for all “beneficial uses”. Beneficial uses provides a basis for the derivation of water quality guidelines, which, for South Africa, are defined in Water quality guidelines for the South African coastal zone (DWAF, 1991). The CSIR has developed a practical approach to marine water quality management, taking into account international trends and local experience, which can be applied to any coastal development with potential influence on water quality. The management plan is divided into three logical components, i.e. • site-specific statutory requirements and environmental objectives; • system design with specific reference to influences on water quality; and • monitoring programmes. Within this management approach water quality issues are addressed in a holistic manner, through focused procedures and clear identification of information requirements. This paper describes the procedures and information requirements within each component of the water quality management plan, with specific reference to marine disposal systems. Ideally, the management plan should be implemented from the feasibility and conceptual design phase of a development and the timing of the different procedures within the development process are therefore also highlighted. However, the logical lay-out of procedures allows for easy initiation (even to existing disposal system) at any stage of development.


Author(s):  
Benjamin A. Musa Bandowe ◽  
Nosir Shukurov ◽  
Sophia Leimer ◽  
Michael Kersten ◽  
Yosef Steinberger ◽  
...  

AbstractThe concentrations, composition patterns, transport and fate of PAHs in semi-arid and arid soils such as in Central Asia are not well known. Such knowledge is required to manage the risk posed by these toxic chemicals to humans and ecosystems in these regions. To fill this knowledge gap, we determined the concentrations of 21 parent PAHs, 4,5-methylenephenanthrene, 6 alkylated PAHs, and biphenyl in soils from 11 sampling locations (0–10, 10–20 cm soil depths) along a 20-km transect downwind from the Almalyk metal mining and metallurgical industrial complex (Almalyk MMC), Uzbekistan. The concentrations of Σ29 PAHs and Σ16 US-EPA PAHs were 41–2670 ng g−1 and 29–1940 ng g−1, respectively. The highest concentration of Σ29 PAHs occurred in the immediate vicinity of the copper smelting factory of the Almalyk MMC. The concentrations in topsoil decreased substantially to a value of ≤ 200 ng g−1 (considered as background concentration) at ≥ 2 km away from the factory. Low molecular weight PAHs dominated the PAH mixtures at less contaminated sites and high molecular weight PAHs at the most contaminated site. The concentration of Σ16 US-EPA PAHs did not exceed the precautionary values set by the soil quality guidelines of, e.g., Switzerland and Germany. Similarly, the benzo[a]pyrene equivalent concentration in soils near the Almalyk MMC did not exceed the value set by the Canadian guidelines for the protection of humans from carcinogenic PAHs in soils. Consequently, the cancer risk due to exposure to PAHs in these soils can be considered as low.


Author(s):  
Jeremy A. Hartsock ◽  
Jessica Piercey ◽  
Melissa K. House ◽  
Dale H. Vitt

AbstractThe experimental Sandhill Wetland is the first permanent reclamation of a composite tailings deposit, and annual water quality monitoring is of specific interest for evaluating and predicting long-term reclamation performance. Here, we present water chemistry monitoring data obtained from Sandhill Wetland (years 2009–2019) and compare results to twelve natural reference wetlands and to environmental quality guidelines for Alberta surface waters. By comparing water quality at Sandhill Wetland and natural sites to established guidelines, we can begin to document the natural background water quality of wetlands in the region and examine if guideline exceedances are seen in natural undisturbed environments, or appear only at active reclamation sites. At Sandhill Wetland the dominant ions in near-surface water were bicarbonate, sulfate, chloride, sodium, calcium, and magnesium. Since the first growing season concentrations for these ions have increased annually, causing concurrent increases in electrical conductivity. In year 2019, water chemistry at Sandhill Wetland was most comparable to regional saline fens, systems that exhibit elevated electrical conductivity and high sodicity. Near-surface water at Sandhill Wetland exceeded water quality guidelines for three substances/properties (dissolved chloride, iron, and total alkalinity) in the most recent year of monitoring. The saline fen natural sites also exceeded water quality guidelines for the same chemical substances/properties, suggesting guideline exceedances are a norm for some natural wetland site types in the region. Of note, in each year of monitoring at Sandhill Wetland, dissolved organic compounds evaluated in sub- and near-surface water were below detection limits.


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