PBL (Problem-Based Learning) method is to problem for based of a method, teaching process in the teachers boot students based on specific problem read information, and organization discussion, eventually boot students to analysis problem and settlement problem; in human anatomy teaching in the application PBL method, change has traditional teaching means, enhanced has students of learning consciousness and sense, improve has students multi cognitive and overall thinking capacity, in students of active participation in the training they of team spirit At the same time flexible application of modern information technology, improving organizational communication skills; The proper application of PBL teaching theory to teaching human anatomy to improve student interest in learning, improve teaching effectiveness, and lay a solid foundation for the future of PBL teaching other courses.