Relation Between Childhood Maltreatment and Severe Intrafamilial Male-Perpetrated Physical Violence in Chinese Community: The Mediating Role of Borderline and Antisocial Personality Disorder Features

2011 ◽  
Vol 38 (1) ◽  
pp. 64-76 ◽  
Author(s):  
Na Liu ◽  
Yalin Zhang ◽  
Heward John Brady ◽  
Yuping Cao ◽  
Ying He ◽  
...  
Keyword(s):  
Personality Disorder ◽  
Antisocial Personality Disorder ◽  
Childhood Maltreatment ◽  
Physical Violence ◽  
Antisocial Personality ◽  
Chinese Community ◽  
Mediating Role

scholarly journals Oxytocin Receptor Gene, Childhood Maltreatment and Borderline Personality Disorder Features among Male Inmates in China

2020 ◽  
Author(s):  
Min Zhang ◽  
Na Liu ◽  
Haocheng Chen ◽  
Ning Zhang
Keyword(s):  
Sexual Abuse ◽  
Borderline Personality Disorder ◽  
High Risk ◽  
Personality Disorder ◽  
Antisocial Personality Disorder ◽  
Childhood Maltreatment ◽  
Oxytocin Receptor ◽  
Borderline Personality ◽  
Antisocial Personality ◽  
Male Inmates

Abstract Background: Borderline personality disorder (BPD) is caused by a variety of biological and environmental factors. Accumulating evidence suggests that childhood maltreatment is a risk environmental factor in the development of BPD, but research on the genetic pathology of BPD is still in its early stages, and very little is known about the oxytocin receptor (OXTR) gene. The purpose of this study is to further explore the interactive effects between OXTR gene polymorphisms and childhood maltreatment on BPD risk. Methods: Among the 1804 male inmates, 765 inmates who had BPD or antisocial personality disorder (ASPD) or highly impulsive or violent crime were considered as high-risk inmates and included in this study. Childhood maltreatment, BPD, antisocial personality disorder (ASPD) and impulsivity were measured by self-reported questionnaires. Peripheral venous blood was collected for the genotype test. Results: Analyses revealed that the BP group (inmates with BPD features) had higher rs53576 AA genotype frequency and rs237987 AA genotype frequency than the non-BP group, while the statistical significances were lost after Bonferroni correction. Total childhood maltreatment score, emotional abuse and neglect could positively predict BPD risk. Among the high-risk samples, rs53576 GG genotype carriers had higher BPD scores at higher levels of physical abuse and sexual abuse and had lower BPD scores at lower levels of physical abuse and sexual abuse. Conclusions: The findings suggest that the interaction between OXTR gene variations and childhood maltreatment is an important mechanism for the development of BPD. The moderating role of the OXTR gene provides evidence for gene plasticity.

Intergenerational transmission of antisocial personality disorder: Maternal role and its declination

2017 ◽  
Vol 41 (S1) ◽  
pp. S586-S586 ◽  
Author(s):  
E. Di Giacomo ◽  
M. Clerici
Keyword(s):  
Personality Disorder ◽  
Intergenerational Transmission ◽  
Antisocial Personality Disorder ◽  
Antisocial Personality ◽  
Maternal Role ◽  
Environmental Implications ◽  
Self Reflection ◽  
Established Disease ◽  
Competing Interest

Antisocial personality disorder is a well-established disease which features space from cruelty to lack of empathy and remorse. Its etiology has been deeply analyzed both for genetic and environmental implications. The role of family context has been underlined throughout the whole psychopathology as an explanation to the etiological conflict between nature and nurture. Even if this conflict seems to be apparently solved, it is still possible to ponder about family implications in terms of causes and consequences. In the antisocial field, maternal role may offer interesting and surprising food for thought. Even if it is commonly believed an intergenerational transmission of aberrant behaviors, particularly in terms of learning behaviors and lack of empathy assimilation, it exists a side part of maternal pathological expression that may play a role in the intergenerational transmission and it is extremely difficult to be detected. Female declination of this disorder may be expressed also through somatic implications and complaints, leading to the hypothesis of a self-reflection of the lack of consideration for other's needs, which is distinctive. It is of extreme importance, particularly in terms of prevention, to consider and identify these connotations of the disorder to be able to try to interrupt the cycle of transmission through generations.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Childhood maltreatment and prospectively observed quality of early care as predictors of antisocial personality disorder features

2012 ◽  
Vol 33 (1) ◽  
pp. 55-69 ◽  
Author(s):  
Zhenyu Shi ◽  
Jean-Francois Bureau ◽  
M. Ann Easterbrooks ◽  
Xudong Zhao ◽  
Karlen Lyons-Ruth
Keyword(s):  
Personality Disorder ◽  
Antisocial Personality Disorder ◽  
Childhood Maltreatment ◽  
Antisocial Personality ◽  
Early Care

Impulsiveness, Impulsive Aggression, Personality Disorder, and Spousal Violence

2003 ◽  
Vol 18 (1) ◽  
pp. 3-14 ◽  
Author(s):  
Daniel W. Edwards ◽  
Charles L. Scott ◽  
Richard M. Yarvis ◽  
Cheryl L. Paizis ◽  
Matthew S. Panizzon
Keyword(s):  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Antisocial Personality Disorder ◽  
Physical Aggression ◽  
Personality Assessment ◽  
Physical Violence ◽  
Borderline Personality ◽  
Antisocial Personality ◽  
Violence Prediction ◽  
Impulsive Aggression

Impulsiveness has become a key concept in thinking about the determinants of violence and aggression. In this study of spouse abusers, the relationship between impulsiveness, impulsive aggression, and physical violence is confirmed. Impulsiveness and impulsive aggression have significant correlations with physical aggression. Impulsiveness and impulsive aggression are also correlated with measures of Borderline Personality Disorder and Antisocial Personality Disorder. In addition, the measures of Borderline and Antisocial Personality Disorder (PD) are significantly correlated with physical aggression. The violent and non-violent groups differed on impulsive aggression and on Borderline Personality Disorder. A partial replication of Tweed and Dutton’s findings (1998) revealed sub-groups of high- and low-violence men. The high-violence group was very different from the low-violent and the non-violent groups. The high-violence group had higher pathology scores on all clinical scales, except Mania, of the Personality Assessment Inventory. These findings have implications for violence prediction and for treatment of violent men.

scholarly journals ARE CHILDHOOD CRUELTY TO ANIMALS INDICATES AS MENTAL DISORDER?

2021 ◽  
Vol 3 (1) ◽  
pp. 56-72
Author(s):  
Risa Juliadilla ◽  
Nia Anggri Noveni
Keyword(s):  
Personality Disorder ◽  
Conduct Disorder ◽  
Character Education ◽  
Antisocial Personality Disorder ◽  
Developmental Psychology ◽  
Animal Cruelty ◽  
Antisocial Personality ◽  
Pros And Cons ◽  
Cruelty To Animals

Animal Cruelty regularly happened during childhood that indicates beyond cruelty to humans. Cruelty to animals distinguishes some steps: curiosity, exploration, imitates or even the aggressive act refers to animal cruelty. The ignorance toward these aggressive acts led to Conduct Disorder or even Antisocial Personality Disorder. Animal Cruelty reached an agreement as to the unethical act with intentional tortures, unintentionally suffering causes death. Cruelty is done on purpose and with intentional time. This research aims as a reference for animal cruelty in childhood by proposing some research summary in (1) Animal Cruelty framework, (2) Animal Cruelty relation among child abuse and domestic violence; (3) Developmental Psychology reference: Children aggressive acts toward animal; (4) animal cruelty and psychology disorder and (5) clinical pathway childhood cruelty to animals. The research conducts a literature review by describing a theory, discussion, and results from textbooks, articles, and journals. The researcher analyzed, compared the results taken from some literature, identifies the pros and cons, and proposing findings and discussions. In conclusion, animal cruelty defines as a crucial marker for mental health that relates to Conduct Disorder to Antisocial Personality Disorder. The role of adults is vital in minimizing children's acts for committing animal cruelty by nurturing empathy. Adults with its role particularly required during the early stages of a child's development when adults' affirmation related to behavioral aspects of morality is necessary for children. Furthermore, character education for children consider as broad topics that not only about the animals, but the most important thing is for animals when children would learn justice, and ethics to treat animals generously.   Keywords: Animal Cruelty, Childhood, Conduct Disorder, Antisocial Personality Disorder  

EEG Does Not Predict Response to Valproate Treatment of Aggression in Patients with Borderline and Antisocial Personality Disorders

2003 ◽  
Vol 34 (2) ◽  
pp. 84-86 ◽  
Author(s):  
Roy R. Reeves ◽  
Frederick A. Struve ◽  
Gloria Patrick
Keyword(s):  
Personality Disorder ◽  
Aggressive Behavior ◽  
Personality Disorders ◽  
Antisocial Personality Disorder ◽  
Antisocial Personality ◽  
Eeg Abnormalities

Previous investigations of the role of EEG in predicting response of aggressive patients to valproate therapy have yielded mixed results. In this study of borderline and antisocial personality disorder patients hospitalized with aggressive behavior, EEGs were obtained prior to treatment with valproate. Eight of 22 (36.4%) patients subsequently responsive to valproate had nonepileptiform EEG abnormalities, while 5 of 20 (25%) patients not responsive to valproate had nonepileptiform EEG abnormalities. Although more of the valproate responders than nonresponders had EEG abnormalities, the presence of nonepileptiform EEG abnormalities was not a statistically significant (X2 = 0.213, df = 1, p = 0.64) predictor of valproate response in personality disorder patients with aggression.

scholarly journals The interaction between monoamine oxidase A (MAOA) and childhood maltreatment as a predictor of personality pathology in females: Emotional reactivity as a potential mediating mechanism

2018 ◽  
Vol 31 (1) ◽  
pp. 361-377 ◽  
Author(s):  
Amy L. Byrd ◽  
Stephen B. Manuck ◽  
Samuel W. Hawes ◽  
Tayler J. Vebares ◽  
Vishwajit Nimgaonkar ◽  
...  
Keyword(s):  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Antisocial Personality Disorder ◽  
Childhood Maltreatment ◽  
Emotional Reactivity ◽  
Borderline Personality ◽  
Monoamine Oxidase A ◽  
Personality Pathology ◽  
Antisocial Personality ◽  
Gene Environment

AbstractResearch consistently demonstrates that common polymorphic variation in monoamine oxidase A (MAOA) moderates the influence of childhood maltreatment on later antisocial behavior, with growing evidence that the “risk” allele (high vs. low activity) differs for females. However, little is known abouthowthis Gene × Environment interaction functions to increase risk, or if this risk pathway is specific to antisocial behavior. Using a prospectively assessed, longitudinal sample of females (n= 2,004), we examined whether changes in emotional reactivity (ER) during adolescence mediated associations between this Gene × Environment and antisocial personality disorder in early adulthood. In addition, we assessed whether this putative risk pathway also conferred risk for borderline personality disorder, a related disorder characterized by high ER. While direct associations between early maltreatment and later personality pathology did not vary by genotype, there was a significant difference in the indirect path via ER during adolescence. Consistent with hypotheses, females with high-activityMAOAgenotype who experienced early maltreatment had greater increases in ER during adolescence, and higher levels of ER predicted both antisocial personality disorderandborderline personality disorder symptom severity. Taken together, findings suggest that the interaction betweenMAOAand early maltreatment places women at risk for a broader range of personality pathology via effects on ER.

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