EEG Does Not Predict Response to Valproate Treatment of Aggression in Patients with Borderline and Antisocial Personality Disorders

2003 ◽  
Vol 34 (2) ◽  
pp. 84-86 ◽  
Author(s):  
Roy R. Reeves ◽  
Frederick A. Struve ◽  
Gloria Patrick

Previous investigations of the role of EEG in predicting response of aggressive patients to valproate therapy have yielded mixed results. In this study of borderline and antisocial personality disorder patients hospitalized with aggressive behavior, EEGs were obtained prior to treatment with valproate. Eight of 22 (36.4%) patients subsequently responsive to valproate had nonepileptiform EEG abnormalities, while 5 of 20 (25%) patients not responsive to valproate had nonepileptiform EEG abnormalities. Although more of the valproate responders than nonresponders had EEG abnormalities, the presence of nonepileptiform EEG abnormalities was not a statistically significant (X2 = 0.213, df = 1, p = 0.64) predictor of valproate response in personality disorder patients with aggression.

2019 ◽  
Vol 33 (1) ◽  
pp. 22-48 ◽  
Author(s):  
Ashley L. Watts ◽  
Madeline G. Nagel ◽  
Robert D. Latzman ◽  
Scott O. Lilienfeld

We examined the relations between: (1) narcissism, psychopathy, DSM-5 personality disorder symptom counts; and (2) paraphilic interests among undergraduates (N = 608). Base rates of paraphilic interests were appreciable. The disinhibition and meanness features of psychopathy and the entitlement and exploitativeness features of narcissism were robustly associated with paraphilic interests, particularly sexual sadism, whereas the boldness features of narcissism and psychopathy were essentially unrelated to these interests. Narcissism and psychopathy features typically manifested the most pronounced relations with paraphilic interests, although antisocial personality disorder features were also strong predictors. By and large, these relations were comparable across gender. Lastly, there was no evidence that erotophilia mediated the relations between the narcissism and psychopathy features and paraphilic interests, most likely because erotophilia was generally unrelated to paraphilic interests. Relative to other dimensions of personality disorders, facets of meanness and disinhibition from psychopathy and entitlement/exploitativeness facets from narcissism were most associated with paraphilic interests.


2017 ◽  
Vol 41 (S1) ◽  
pp. S586-S586 ◽  
Author(s):  
E. Di Giacomo ◽  
M. Clerici

Antisocial personality disorder is a well-established disease which features space from cruelty to lack of empathy and remorse. Its etiology has been deeply analyzed both for genetic and environmental implications. The role of family context has been underlined throughout the whole psychopathology as an explanation to the etiological conflict between nature and nurture. Even if this conflict seems to be apparently solved, it is still possible to ponder about family implications in terms of causes and consequences. In the antisocial field, maternal role may offer interesting and surprising food for thought. Even if it is commonly believed an intergenerational transmission of aberrant behaviors, particularly in terms of learning behaviors and lack of empathy assimilation, it exists a side part of maternal pathological expression that may play a role in the intergenerational transmission and it is extremely difficult to be detected. Female declination of this disorder may be expressed also through somatic implications and complaints, leading to the hypothesis of a self-reflection of the lack of consideration for other's needs, which is distinctive. It is of extreme importance, particularly in terms of prevention, to consider and identify these connotations of the disorder to be able to try to interrupt the cycle of transmission through generations.Disclosure of interestThe authors have not supplied their declaration of competing interest.


Criminologie ◽  
2005 ◽  
Vol 27 (2) ◽  
pp. 33-53 ◽  
Author(s):  
Jean Proulx ◽  
Jocelyn Aubut ◽  
Lise Perron ◽  
André McKibben

During the past 30 years, behavioral and cognitive-behavioral theories of rape have evolved considerably. The influence of etio-logic factors related to personality, however, is limited to antisocial traits. The aim of the current study was, therefore, to investigate the presence of personality disorders in rapists. Forty-nine incarcerated rapists answered a French translation of the Millon Clinical Multiaxial Inventory questionnaire. On the basis of the Avery-Clark and Laws criteria (1983), 31 rapists were classified as less physically violent and 18 as more physically violent. Among the less physically violent rapists, we encountered most frequently avoidant, dependant, passive-aggressive and schizoid personality disorders. Among the more physically violent rapists, an antisocial personality disorder was predominant. The implications of these results concerning rape theories are being discussed.


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