scholarly journals Role of road traffic accidents and other traumatic events in the onset of chronic widespread pain: Results from a population-based prospective study

2011 ◽  
Vol 63 (5) ◽  
pp. 696-701 ◽  
Author(s):  
Gareth T. Jones ◽  
Barbara I. Nicholl ◽  
John McBeth ◽  
Kelly A. Davies ◽  
Richard K. Morriss ◽  
...  
2014 ◽  
Vol 9 (1) ◽  
pp. 30-39
Author(s):  
D Chapagain ◽  
D Jayapal Reddy ◽  
S Shah ◽  
KG Shrestha

Objectives: Thoracic injury is a challenge to the thoracic surgeon practicing in developing countries. This prospective study was conducted to see the mode of injury, injury types and overall outcome of thoracic injury in our settings. Materials and methods: This prospective study was conducted in 100 thoracic injury patients between December 2011 to June 2012. The demographic features, type of the trauma, radiological assessment, associated organ injuries, management of the injury, surgical interventions, morbidity, mortality, length of hospital stay were analysed. Results: In this study the ages ranged from 7 to 84 years. There were 73 (73%) males and 27 (27%) females. The majority of patients (83%) were injured during the evening and night time. The majority of patients 92(92%) sustained blunt chest injuries. The mechanism of injury was not significantly associated with length of hospital stay (P > 0.05) and mortality (P > 0.05).Road traffic accident was the most common cause of injuries affecting 68(68%) of patients followed by fall injury of 19(19%). Rib fractures, haemothorax, pneumothorax and lung contusion were the most common type of injuries accounting for 83.0%, 57%,34% and 33% respectively. Associated extra-thoracic injuries were noted in 64.0% of patients. 45(45%) of the cases of haemothorax, pneumotharax and haemopneumothorax were treated by tube thoracotomy. Four patients (04%) had undergone thoracotomy. There were 09(09%) patients of flail chest and treated conservatively. Fourty six patients (46%) were admitted in the ICU. Eleven (11%) patients were treated with ventilator support. Seventeen (17%) patients had complication. The overall length of hospital stay ranged from 0 to 25 days. Conclusion: Road traffic accidents and fall from height are the major public health problems. Preventive measures at reducing road traffic accidents and timely management with closed tube thoracotomy are the main factors to be considered in the thoracic injury. Journal of College of Medical Sciences-Nepal, 2013, Vol-9, No-1, 30-39 DOI: http://dx.doi.org/10.3126/jcmsn.v9i1.9671


2010 ◽  
Vol 69 (11) ◽  
pp. 2009-2012 ◽  
Author(s):  
Barbara I Nicholl ◽  
Kate L Holliday ◽  
Gary J Macfarlane ◽  
Wendy Thomson ◽  
Kelly A Davies ◽  
...  

ObjectivesThe aim of this study was to investigate the association between the catechol-O-methyltransferase (COMT) ‘pain sensitivity’ haplotypes and chronic widespread pain (CWP) in two distinct cohorts.MethodsCases of CWP and controls free of pain were selected from two population-based studies: the Epidemiology of Functional Disorders study (EPIFUND) (UK) and the European Male Ageing Study (European). The number of cases and controls were 164 and 172, and 204 and 935, respectively. Identical American College of Rheumatology criteria were used in both studies to ascertain CWP status. The EPIFUND study had three time points and cases were classified as subjects with CWP at two or three time points and controls as those free of pain at all three time points. Four single nucleotide polymorphisms (SNP): rs6269, rs4633, rs4818 and rs4680 (V158M) were genotyped using Sequenom technology. Allele and genotype frequencies were compared and haplotype analysis was conducted using PLINK software.ResultsNo differences in allele or genotype frequencies for any of the four SNP were observed between cases and controls for either cohort. Haplotype analysis also showed no difference in the frequency of haplotypes between cases and controls.ConclusionsThere was no evidence of association between the COMT ‘pain sensitivity’ haplotypes and CWP in two population-based cohorts.


2018 ◽  
Vol 7 (3) ◽  
pp. 92
Author(s):  
SeyedSaeed Hashemi Nazari ◽  
Fatemeh Shahbazi ◽  
Hamid Soori ◽  
Soheila Khodakarim ◽  
MohammadReza Ghadirzadeh ◽  
...  

Author(s):  
Moustafa Moustafa ◽  
B. Serpil Acar ◽  
Memis Acar

The aim of this study is to investigate the possible role of placental location on the risk of placental abruption in road traffic accidents involving a pregnant driver. Placental abruption accounts for around 50–70% of fetal deaths in motor vehicle accidents. The computational pregnant occupant model, ‘Expecting’, which has a multi-body fetus and a finite element uterus model was developed at Loughborough University and is used in this investigation. The placenta is located in the upper region of the uterus near the fundus in ‘Expecting’. Four locations for the placenta; anterior, posterior, lateral left, lateral right cases are modelled and used in simulations in this study. These models are used to simulate a range of frontal impacts of severity 15 kph and 30 kph. Three cases of occupant restraint: three-point seatbelt with an airbag, three-point seatbelt only and airbag only conditions are investigated. The maximum strains developed in the uterus and utero-placental interface (UPI) have been estimated and compared for these scenarios in order to investigate placental abruption that leads to fetal loss. Placenta located at anterior position is found to be at higher risk than other positions considered.


Author(s):  
Mohammad Mohai El-Din Awad ◽  
Abd-El Raouf Mohamed El-Deib ◽  
Fadia Mostafa Attia ◽  
Mohamed Negm ◽  
Mohamed Hassan Mohamed Soliman ◽  
...  

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