Precise Control of Cell Adhesion by Combination of Surface Chemistry and Soft Lithography

2012 ◽  
Vol 2 (1) ◽  
pp. 95-108 ◽  
Author(s):  
Wenfu Zheng ◽  
Wei Zhang ◽  
Xingyu Jiang
2007 ◽  
Vol 19 (18) ◽  
pp. 4405-4414 ◽  
Author(s):  
Gregory M. Harbers ◽  
Kazunori Emoto ◽  
Charles Greef ◽  
Steven W. Metzger ◽  
Heather N. Woodward ◽  
...  

2000 ◽  
Vol 29 (4) ◽  
pp. 267-273 ◽  
Author(s):  
Milan Mrksich

Langmuir ◽  
2004 ◽  
Vol 20 (10) ◽  
pp. 4155-4161 ◽  
Author(s):  
Christina J. Lee ◽  
Mark S. Blumenkranz ◽  
Harvey A. Fishman ◽  
Stacey F. Bent

2019 ◽  
Vol 11 (17) ◽  
pp. 15411-15416 ◽  
Author(s):  
Jeffrey W. Chen ◽  
Kelly Lim ◽  
Stephen B. Bandini ◽  
Greg M. Harris ◽  
Joshua A. Spechler ◽  
...  

2016 ◽  
Vol 8 (10) ◽  
pp. 6344-6353 ◽  
Author(s):  
Enrique Martínez-Campos ◽  
Tamara Elzein ◽  
Alice Bejjani ◽  
Maria Jesús García-Granda ◽  
Ana Santos-Coquillat ◽  
...  

2007 ◽  
Vol 1002 ◽  
Author(s):  
Daniel Gallego ◽  
Nicholas J. Ferrell ◽  
Derek J. Hansford

ABSTRACTA method for the fabrication of piezoelectric polyvinylidene fluoride (PVDF) microstructures is described. Embossed and individual features with highly defined geometries at the microscale were obtained using soft lithography-based techniques. Various structure geometries were obtained, including pillars (three different aspect ratios), parallel lines, and criss-crossed lines. SEM characterization revealed uniform patterns with dimensions ranging from 2 μm ñ 15 μm. Human osteosarcoma (HOS) cell cultures were used to evaluate the cytocompatibility of the microstructures. SEM and fluorescence microscopy showed adequate cell adhesion, proliferation, and strong interaction with tips and corners of the microdiscontinuities. Microfabricated piezoelectric PVDF structures could find applications in the fabrication of mechanically active tissue engineering scaffolds, and the development of dynamic sensors at the cellular and subcellular levels.


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