Light-triggered intracellular delivery of a protein toxin was achieved by codelivery via a liposomal nanocarrier, targeted with a cell-penetrating peptide (CPP)–photosensitiser conjugate.
A convenient and efficient method for intracellular delivery of a water-soluble anionic porphyrin has been developed by utilizing its supramolecular interaction with per-O-methyl-β-cyclodextrin bearing an octaarginine chain as a cell-penetrating peptide.
Development of a cell-penetrating peptide library to deliver biomolecules affecting mitochondria functionalities by targeting genes coding for mitochondrial proteins.
Pore-enlarged 3D cubic cMSNs were successfully prepared, and their surfaces were functionalized by a cell-penetrating R8-peptide through the click reaction for cytosolic delivery of a functional protein in its native form.
The conjugate of autophagy-inducing peptide with cell-penetrating peptide formed by hybridization between peptide nucleic acids was delivered into cell and induced effective autophagy.