In vitro effects of gammaglobulin (IgG) on human monocyte Fc receptor function. I. Effect on monocyte membrane-associated IgG and Fc receptor-dependent binding of antibody-coated platelets

1986 ◽  
Vol 23 (3) ◽  
pp. 197-207 ◽  
Author(s):  
Mansoor N. Saleh ◽  
Wayne S. Court ◽  
Albert F. Lobuglio
Keyword(s):  
Human Monocyte ◽  
Fc Receptor ◽  
Receptor Function ◽  
In Vitro Effects

scholarly journals Augmentation of macrophage complement receptor function in vitro. I. Characterization of the cellular interactions required for the generation of a T-lymphocyte product that enhances macrophage complement receptor function.

1979 ◽  
Vol 150 (3) ◽  
pp. 653-675 ◽  
Author(s):  
J A Griffin ◽  
F M Griffin
Keyword(s):  
T Lymphocytes ◽  
Complex Disease ◽  
Peritoneal Macrophages ◽  
Fc Receptor ◽  
Microbial Pathogens ◽  
Complement Receptor ◽  
Complement Receptors ◽  
Cellular Interactions ◽  
Receptor Function

The function of complement receptors of mouse peritoneal macrophages was converted in vitro from mediating only attachment of macrophage complement receptor function was achieved by treating freshly explanted macrophages with supernates from cultures containing T lymphocytes and appropriately triggered macrophages. Fc receptor-mediated phagocyctosis by macrophages was required for the production of active supernates, for neither ingestion via the cells' complement receptors nor ingestion via nonimmunologic means was a sufficient stimulus for the macrophages' participation in the generation of supernatant activity. Fc receptor-triggered macrophages interacted by a contact dependent, but histocompatibility independent, mechanism with T lymphocytes, thereby signalling the lymphocytes to elaborate the active product. The possible significance of enhanced macrophage complement receptor function in inflammation, host defense against microbial pathogens, immune complex disease, and neoplasia is discussed.

scholarly journals In vitro effects of cefotaxime and ceftriaxone on Salmonella typhi within human monocyte-derived macrophages

2002 ◽  
Vol 8 (12) ◽  
pp. 810-813 ◽  
Author(s):  
B. Ekinci ◽  
A.Y. Coban ◽  
A. Birinci ◽  
B. Durupinar ◽  
M. Erturk
Keyword(s):  
Human Monocyte ◽  
Salmonella Typhi ◽  
In Vitro Effects

In vitro effects of dihydrotestosterone (DHT) on gonadotropin receptor function and steroidogenesis in human granulosa lutein cells

2021 ◽  
Author(s):  
Priyanka Anujan ◽  
Lisa Owens ◽  
Botkjaer Jane Alro ◽  
Aylin Hanyaloglu ◽  
Kate Hardy ◽  
...  
Keyword(s):  
Receptor Function ◽  
Gonadotropin Receptor ◽  
In Vitro Effects

In vitro study of Fc-receptor function in autoimmune diseases

1985 ◽  
Vol 9 (1) ◽  
pp. 53-56 ◽  
Author(s):  
D. Roccatello ◽  
J.C. Bensa ◽  
R. Coppo ◽  
C. Rollino ◽  
M. Diaz ◽  
...  
Keyword(s):  
Autoimmune Diseases ◽  
In Vitro Study ◽  
Fc Receptor ◽  
Vitro Study ◽  
Receptor Function

scholarly journals In vivo activation of macrophage C3 receptors for phagocytosis.

1985 ◽  
Vol 162 (1) ◽  
pp. 352-357 ◽  
Author(s):  
F M Griffin ◽  
P J Mullinax
Keyword(s):  
T Lymphocytes ◽  
Immune Complexes ◽  
Fc Receptors ◽  
Peritoneal Macrophages ◽  
Fc Receptor ◽  
Athymic Mice ◽  
Receptor Function ◽  
C3 Receptors

We assessed the effects of exposure to immune complexes in vivo on macrophages' Fc receptor function and C3 receptor function. Peritoneal macrophages from mice injected intraperitoneally with immune complexes were markedly impaired in their ability to phagocytize via their Fc receptors but had acquired the ability to phagocytize via their C3 receptors. In vivo activation of macrophages' C3 receptors for phagocytosis required T lymphocytes, because macrophages from athymic mice could not be activated by injection of immune complexes. The requirement for both T lymphocytes and immune complexes for activation of macrophages' C3 receptors in vivo is identical to the requirements for activation of macrophages' C3 receptors in vitro, suggesting that the mechanisms we have identified for activation of these receptors in vitro are the same mechanisms by which the receptors are activated for phagocytosis in vivo. The susceptibility of macrophages' Fc receptors to blockade by immune complexes and the activation of their C3 receptors for phagocytosis in a milieu containing immune complexes suggest that it may be macrophages' C3 receptors, not their Fc receptors, that are primarily responsible for promoting phagocytosis of opsonized microorganisms in immune hosts.

scholarly journals Effects of immune complexes from SLE patients on human monocyte locomotion and Fc receptor function.

1984 ◽  
Vol 43 (5) ◽  
pp. 729-733 ◽  
Author(s):  
K Lukacs ◽  
M Kavai ◽  
A Banyai ◽  
I Sonkoly ◽  
E Vegh ◽  
...  
Keyword(s):  
Immune Complexes ◽  
Human Monocyte ◽  
Fc Receptor ◽  
Receptor Function
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