Comment on prevalence of hereditary prosopagnosia (HPA) in Hong Kong Chinese population

2008 ◽  
Vol 146A (22) ◽  
pp. 2860-2862 ◽  
Author(s):  
Bradley Duchaine
Keyword(s):  
Hong Kong ◽  
Chinese Population ◽  
Hong Kong Chinese

scholarly journals Patterns of antihypertensive prescribing, discontinuation and switching among a Hong Kong Chinese population from over one million prescriptions

2008 ◽  
Vol 22 (10) ◽  
pp. 714-716 ◽  
Author(s):  
M C S Wong ◽  
J Y Jiang ◽  
A T Lam ◽  
H Fung ◽  
S Griffiths ◽  
...  
Keyword(s):  
Hong Kong ◽  
Chinese Population ◽  
Hong Kong Chinese

Recurrence After a First Untreated Seizure in the Hong Kong Chinese Population

Epilepsia ◽  
2008 ◽  
Vol 42 (1) ◽  
pp. 94-97 ◽  
Author(s):  
A. C. F. Hui ◽  
A. Tang ◽  
K. S. Wong ◽  
V. Mok ◽  
R. Kay
Keyword(s):  
Hong Kong ◽  
Chinese Population ◽  
Hong Kong Chinese

scholarly journals Genetic Analysis of the CYP2D6 Locus in a Hong Kong Chinese Population

2000 ◽  
Vol 46 (1) ◽  
pp. 18-23 ◽  
Author(s):  
Mercè Garcia-Barceló ◽  
Lok Yee Chow ◽  
Helen Fung Kum Chiu ◽  
Yun Kowk Wing ◽  
Dominic Tak Shing Lee ◽  
...  
Keyword(s):  
Hong Kong ◽  
Chinese Population ◽  
Hong Kong Chinese ◽  
Enzyme Analysis ◽  
Restriction Enzyme Analysis ◽  
Chinese Populations ◽  
Specific Pcr ◽  
Significant Difference ◽  
Exon 1 ◽  
Allele Specific

Abstract Background: The cytochrome P450 CYP2D6 enzyme debrisoquine 4-hydroxylase metabolizes many different classes of commonly used drugs, such as tricyclic antidepressants and neuroleptics. Genetic polymorphism of the CYP2D6 gene is responsible for pronounced interindividual and interracial differences in the metabolism of these drugs. The CYP2D6*10 allele and its variants are the most frequent alleles found in Orientals, and they are responsible for diminished debrisoquine 4-hydroxylase activity because of the presence of a C188→T mutation in exon 1. Methods: One hundred nineteen Hong Kong Chinese subjects were genotyped by means of allele-specific PCR, PCR, and restriction enzyme analysis for 10 CYP2D6 alleles (CYP2D6*1, *2, *4D, *5, *8/*14, *10A, *10B, *15, *16, and J9). Results: CYP2D6*10B was the most prevalent allele, and CYP2D6*10/CYP2D6*10 was the most frequent genotype, representing 46.22% of the population. Conclusions: There was no significant difference in the prevalence of the alleles analyzed between our study and the Chinese populations genotyped previously. This is the largest study in terms of the number of CYP2D6 alleles analyzed in an Oriental population and the first one conducted in a Hong Kong Chinese population.

scholarly journals Serotypes of Escherichia coli isolated from patients with recurrent pyogenic cholangitis

1982 ◽  
Vol 88 (3) ◽  
pp. 513-517 ◽  
Author(s):  
W. T. Wong ◽  
K. A. Bettelheim ◽  
F. C. Y. Cheng ◽  
G. B. Ong
Keyword(s):  
Escherichia Coli ◽  
Hong Kong ◽  
Chinese Population ◽  
Hong Kong Chinese ◽  
Chinese Patients ◽  
Recurrent Pyogenic Cholangitis

SummaryStrains of Escherichia coli were isolated from laparotomy specimens from Chinese patients with recurrent pyogenic cholangitis in Hong Kong. A large variety of serotypes were found. Several sites were sampled in each patient. While only one serotype was normally isolated from one site, different sites often yielded different serotypes in the same patient. Generally the ‘O’ types found did not correspond to those found in the faeces of the Hong Kong Chinese population.

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