scholarly journals Plasma neurofilament light chain (NfL) relates to preclinical changes in cognition, structural white matter integrity and markers of cerebral small‐vessel disease: A population‐based study

2021 ◽  
Vol 17 (S5) ◽  
Author(s):  
Joyce van Arendonk ◽  
Frank J. Wolters ◽  
Julia Neitzel ◽  
Elisabeth J. Vinke ◽  
Meike W. Vernooij ◽  
...  
Keyword(s):  
White Matter ◽  
Light Chain ◽  
Small Vessel Disease ◽  
Population Based ◽  
Cerebral Small Vessel Disease ◽  
White Matter Integrity ◽  
Neurofilament Light Chain ◽  
Population Based Study ◽  
Neurofilament Light ◽  
Vessel Disease

Total Cerebral Small Vessel Disease Score and Anthropometric Indices: A Population-Based Study in Older Adults of Amerindian Ancestry

2021 ◽  
pp. 1-4
Author(s):  
Oscar H. Del Brutto ◽  
Robertino M. Mera
Keyword(s):  
Older Adults ◽  
Small Vessel Disease ◽  
Brain Magnetic Resonance Imaging ◽  
Population Based ◽  
Cerebral Small Vessel Disease ◽  
The Body ◽  
Small Vessel ◽  
Population Based Study ◽  
Vessel Disease ◽  
Ordinal Logistic Regression Model

A total of 590 older adults of Amerindian ancestry living in rural Ecuador received anthropometric measurements and a brain magnetic resonance imaging to estimate the total cerebral small vessel disease (cSVD) score. A fully adjusted ordinal logistic regression model, with categories of the total cSVD score as the dependent variable, disclosed significant associations between the waist circumference, the waist-to-hip, and the waist-to-height ratios – but not the body mass index (BMI) – and the cSVD burden. Indices of abdominal obesity may better correlate with severity of cSVD than the BMI in Amerindians. Phenotypic characteristics of this population may account for these results.

Cerebral small vessel disease is related to disturbed 24-h activity rhythms: a population-based study

2015 ◽  
Vol 22 (11) ◽  
pp. 1482-1487 ◽  
Author(s):  
L. A. Zuurbier ◽  
M. A. Ikram ◽  
A. I. Luik ◽  
A. Hofman ◽  
E. J. W. Van Someren ◽  
...  
Keyword(s):  
Small Vessel Disease ◽  
Population Based ◽  
Cerebral Small Vessel Disease ◽  
Small Vessel ◽  
Population Based Study ◽  
Activity Rhythms ◽  
Vessel Disease

scholarly journals Loss of white matter integrity is associated with gait disorders in cerebral small vessel disease

Brain ◽  
2010 ◽  
Vol 134 (1) ◽  
pp. 73-83 ◽  
Author(s):  
K. F. de Laat ◽  
A. M. Tuladhar ◽  
A. G. W. van Norden ◽  
D. G. Norris ◽  
M. P. Zwiers ◽  
...  
Keyword(s):  
White Matter ◽  
Small Vessel Disease ◽  
Cerebral Small Vessel Disease ◽  
Gait Disorders ◽  
White Matter Integrity ◽  
Small Vessel ◽  
Vessel Disease

scholarly journals In the blood: biomarkers for amyloid pathology and neurodegeneration in Alzheimer’s disease

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Jamie Toombs ◽  
Henrik Zetterberg
Keyword(s):  
Light Chain ◽  
Amyloid Β ◽  
Population Based ◽  
Blood Biomarkers ◽  
Neurofilament Light Chain ◽  
Population Based Study ◽  
Neurofilament Light ◽  
Total Tau ◽  
Amyloid Pathology ◽  
Relationship Of

This scientific commentary refers to ‘Plasma total-tau, neurofilament light chain and amyloid-β levels and risk of dementia: a population-based study’ by de Wolf et al. (https://doi.org/10.1093/brain/awaa054), and ‘Relationship of amyloid-b1–42 in blood and brain amyloid: Ginkgo Evaluation of Memory Study’ by Lopez et al. (https://doi.org/10.1093/braincomms/fcz038), two papers that illustrate these latest developments.

[P2-338]: ARE NEUROFILAMENT LIGHT CHAIN AND WHITE MATTER INTEGRITY RELATED BIOMARKERS FOR FAMILIAL FRONTOTEMPORAL DEMENTIA?

2017 ◽  
Vol 13 (7S_Part_15) ◽  
pp. P751-P752 ◽  
Author(s):  
Jessica L. Panman ◽  
Emma Louise van der Ende ◽  
Lieke H.H. Meeter ◽  
Mark J.R.J. Bouts ◽  
Elise G.P. Dopper ◽  
...  
Keyword(s):  
White Matter ◽  
Frontotemporal Dementia ◽  
Light Chain ◽  
White Matter Integrity ◽  
Neurofilament Light Chain ◽  
Neurofilament Light

scholarly journals Serum Neurofilament Light Chain Levels Are Related to Small Vessel Disease Burden

2018 ◽  
Vol 20 (2) ◽  
pp. 228-238 ◽  
Author(s):  
Marco Duering ◽  
Marek J. Konieczny ◽  
Steffen Tiedt ◽  
Ebru Baykara ◽  
Anil Man Tuladhar ◽  
...  
Keyword(s):  
Light Chain ◽  
Disease Burden ◽  
Small Vessel Disease ◽  
Small Vessel ◽  
Neurofilament Light Chain ◽  
Neurofilament Light ◽  
Vessel Disease
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