scholarly journals Innenrücktitelbild: Magnetically Induced Alignment of Natural Products for Stereochemical Structure Determination via NMR (Angew. Chem. 37/2020)

2020 ◽  
Vol 132 (37) ◽  
pp. 16387-16387
Author(s):  
Niels Karschin ◽  
Klaus Wolkenstein ◽  
Christian Griesinger
Keyword(s):  
Natural Products ◽  
Structure Determination ◽  
Stereochemical Structure

scholarly journals Magnetically Induced Alignment of Natural Products for Stereochemical Structure Determination via NMR

2020 ◽  
Vol 132 (37) ◽  
pp. 15994-15998
Author(s):  
Niels Karschin ◽  
Klaus Wolkenstein ◽  
Christian Griesinger
Keyword(s):  
Natural Products ◽  
Structure Determination ◽  
Stereochemical Structure

Stereochemical structure determination of p-cymene Ru(II) complexes containing the PPh2Py ligand with 2-D NOESY and HMQC NMR experiments

2005 ◽  
Vol 358 (11) ◽  
pp. 3272-3276 ◽  
Author(s):  
Esther de la Encarnación ◽  
Josefina Pons ◽  
Ramón Yáñez ◽  
Josep Ros
Keyword(s):  
Structure Determination ◽  
Stereochemical Structure

Single Crystal X-Ray Structural Determination: A Powerful Technique for Natural Products Research and Drug Discovery

2012 ◽  
Vol 545 ◽  
pp. 3-15
Author(s):  
Hoong Kun Fun ◽  
Suchada Chantrapromma ◽  
Nawong Boonnak
Keyword(s):  
Natural Products ◽  
Drug Discovery ◽  
Single Crystal ◽  
Natural Product ◽  
Structure Determination ◽  
Three Dimensional ◽  
X Ray ◽  
Powerful Technique ◽  
Determination Of Absolute Configuration

Drug discovery from natural products resources have been extensively studied. The most important step in the discovery process is the identification of compounds with interesting biological activity. Single crystal X-ray structure determination is a powerful technique for natural products research and drug discovery in which the detailed three-dimensional structures that emerge can be co-related to the activities of these structures. This article shall present (i) co-crystal structures, (ii) determination of absolute configuration and (iii) the ability to distinguish between whether a natural product compound is a natural product or a natural product artifact. All these three properties are unique to the technique of single crystal X-ray structure determination.

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