scholarly journals A Biomimetic Approach for Spatially Controlled Cell Membrane Engineering Using Fusogenic Spherical Nucleic Acid

2021 ◽  
Author(s):  
Minjie Lin ◽  
Yuanyuan Chen ◽  
Sisi Zhao ◽  
Rui Tang ◽  
Zhou Nie ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Cell Membrane ◽  
Spherical Nucleic Acid ◽  
Biomimetic Approach ◽  
Membrane Engineering

Studies of the uptake of macromolecules by cells. I. Uptake of proteins by cells of the Ehrlich–Lettré ascites carcinoma

1968 ◽  
Vol 46 (12) ◽  
pp. 1443-1450 ◽  
Author(s):  
Y. C. Choi ◽  
E. R. M. Kay
Keyword(s):  
Nucleic Acid ◽  
Cell Membrane ◽  
Binding Sites ◽  
Specific Binding ◽  
Protein Uptake ◽  
Specific Binding Sites ◽  
Model Protein ◽  
Uptake Process ◽  
Kinetics Of ◽  
Protein Treatment

The uptake of protein by cells of the Ehrlich–Lettré ascites carcinoma was characterized kinetically by using hemoglobin as a model protein. An attempt was made to show that the process is not an artefact due to nonspecific adsorption of protein to the cell membrane. The kinetics of the uptake process suggested that an interaction exists between the exogenous protein and specific binding sites on the membrane. Acetylation of hemoglobin enhanced the rate of uptake of this protein. Treatment of cells with neuraminidase, phospholipase A, and Pronase resulted in an inhibition of protein uptake. The experimental evidence for the uptake of hemoglobin was supported by evidence that L-serine-U-14C-labelled hemoglobin is transported into the cytoplasm and utilized subsequently, resulting in labelling of the nucleic acid nucleotides.

scholarly journals Stem cell membrane engineering for cell rolling using peptide conjugation and tuning of cell–selectin interaction kinetics

Biomaterials ◽  
2012 ◽  
Vol 33 (20) ◽  
pp. 5004-5012 ◽  
Author(s):  
Hao Cheng ◽  
Marta Byrska-Bishop ◽  
Cathy T. Zhang ◽  
Christian J. Kastrup ◽  
Nathaniel S. Hwang ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Membrane ◽  
Cell Rolling ◽  
Peptide Conjugation ◽  
Interaction Kinetics ◽  
Membrane Engineering

scholarly journals Polyethylenimine–Spherical Nucleic Acid Nanoparticles against Gli1 Reduce the Chemoresistance and Stemness of Glioblastoma Cells

2018 ◽  
Vol 15 (11) ◽  
pp. 5135-5145 ◽  
Author(s):  
Jilian R. Melamed ◽  
Stephen A. Ioele ◽  
Ariel J. Hannum ◽  
Violet M. Ullman ◽  
Emily S. Day
Keyword(s):  
Nucleic Acid ◽  
Glioblastoma Cells ◽  
Spherical Nucleic Acid

Sortase-A mediated chemoenzymatic lipidation of single-domain antibodies for cell membrane engineering

2020 ◽  
Vol 153 ◽  
pp. 121-129
Author(s):  
Steffen Wöll ◽  
Christopher Bachran ◽  
Stefan Schiller ◽  
Lee Kim Swee ◽  
Regina Scherließ
Keyword(s):  
Cell Membrane ◽  
Single Domain ◽  
Sortase A ◽  
Single Domain Antibodies ◽  
Membrane Engineering

A Spherical Nucleic Acid Probe Based on the Au–Se Bond

2020 ◽  
Vol 92 (12) ◽  
pp. 8459-8463 ◽  
Author(s):  
Peng Gao ◽  
Bo Liu ◽  
Wei Pan ◽  
Na Li ◽  
Bo Tang
Keyword(s):  
Nucleic Acid ◽  
Spherical Nucleic Acid
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